Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13557036 | 1.00 | LMNA (0.42) | LMNATSHRTHRBDNM1MAPT | |
| SCHEMBL4652996 | 1.00 | LMNA (0.42) | LMNATSHRTHRBDNM1MAPT | |
| SCHEMBL9148426 | 0.97 | OPRM1 (0.42) | LMNATSHRTHRBDNM1MAPT | |
| SCHEMBL7626563 | 0.89 | DNM1 (0.39) | LMNATSHRTHRBDNM1OPRM1 | |
| SCHEMBL15087070 | 0.88 | LMNA (0.38) | LMNATSHRTHRBDNM1MAPT | |
| SCHEMBL23981574 | 0.79 | FDPS (0.47) | LMNATSHRTHRBDNM1MAPT | |
| SCHEMBL14127812 | 0.79 | FDPS (0.47) | LMNATSHRTHRBDNM1MAPT | |
| SCHEMBL21308386 | 0.79 | FDPS (0.47) | LMNATSHRTHRBDNM1MAPT | |
| SCHEMBL707693 | 0.77 | TSHR (0.30) | TSHR | |
| SCHEMBL7688271 | 0.77 | MAPT (0.45) | LMNATSHRTHRBDNM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998053361-A2 | POLARIZABLE AMINES AND POLYIMIDES FOR OPTICAL ALIGNMENT OF LIQUID CRYSTALS | ALLIANT TECHSYSTEMS INC. (US) | 1998-11-26 | — | — | WO | disclosed |