Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | TERT | O14746 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | FGB | P02675 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6374241 | 0.87 | MAPT (0.53) | MAPTSMN1; SMN2EGFRMAPK1L3MBTL1 | |
| SCHEMBL6368236 | 0.81 | MAPT (0.50) | MAPTSMN1; SMN2EGFRMAPK1L3MBTL1 | |
| SCHEMBL6366561 | 0.78 | MAPT (0.58) | MAPTSMN1; SMN2EGFRMAPK1L3MBTL1 | |
| SCHEMBL6372364 | 0.76 | MAPT (0.47) | MAPTSMN1; SMN2EGFRMAPK1L3MBTL1 | |
| SCHEMBL4732620 | 0.76 | MAPT (0.64) | MAPTSMN1; SMN2EGFRMAPK1L3MBTL1 | |
| SCHEMBL5605703 | 0.74 | MAPT (0.61) | MAPTSMN1; SMN2EGFRMAPK1L3MBTL1 | |
| SCHEMBL8034804 | 0.74 | MAPT (0.62) | MAPTSMN1; SMN2EGFRMAPK1L3MBTL1 | |
| SCHEMBL27981642 | 0.74 | TOP2B (0.53) | MAPTSMN1; SMN2EGFRMAPK1L3MBTL1 | |
| SCHEMBL1898421 | 0.74 | MAPT (0.53) | MAPTSMN1; SMN2EGFRMAPK1L3MBTL1 | |
| SCHEMBL28814380 | 0.74 | MAPT (0.49) | MAPTSMN1; SMN2EGFRMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | HUANG HSU-SHAN (TW) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | NFE2L2, NR2F2, TFAM | MAPT 4766/4885SMN1; SMN2 1384/4885EGFR 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.