Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029263 | 0.86 | HTR2C (0.57) | HTR2CKDM4EMEN1KMT2AGAA | |
| SCHEMBL4023275 | 0.82 | MEN1 (0.57) | HTR2CPSMB1PSMB5PSMB2MCHR1 | |
| SCHEMBL4267510 | 0.81 | MCHR1 (0.60) | KDM4EMCHR1MEN1KMT2ASLC5A7 | |
| SCHEMBL6200574 | 0.81 | MEN1 (0.55) | HTR2CMCHR1MEN1KMT2ASLC5A7 | |
| SCHEMBL4026160 | 0.80 | ALDH1A1 (0.59) | HTR2CKDM4EMEN1KMT2ATSHR | |
| SCHEMBL3841383 | 0.80 | MAPK1 (0.60) | KDM4EMCHR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL915244 | 0.78 | RAD52 (0.57) | HTR2CKDM4EMCHR1MEN1KMT2A | |
| SCHEMBL3837994 | 0.76 | LTA4H (0.55) | HTR2CPSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL6306251 | 0.76 | LTA4H (0.55) | HTR2CPSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL4270714 | 0.75 | MAPK1 (0.58) | KDM4EMCHR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203079-A1 | Compounds having affinity at 5ht2C receptor and use thereof in therapy | GLAXO GROUP LIMITED | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203079-A1 | Compounds having affinity at 5ht2C receptor and use thereof in therapy | HTR7, HTR2C, HTR3C | HTR2C 2/4885PSMB1 4508/4885PSMB5 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.