Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637183 | 0.82 | SLC6A2 (0.57) | L3MBTL1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL10370952 | 0.80 | ALDH1A1 (0.49) | L3MBTL1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL11729549 | 0.80 | ALDH1A1 (0.53) | L3MBTL1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL11631375 | 0.80 | L3MBTL1 (0.62) | L3MBTL1SMN1; SMN2GAAALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL28544066 | 0.78 | L3MBTL1 (0.60) | L3MBTL1SMN1; SMN2GAAALDH1A1HTT | |
| SCHEMBL5429300 | 0.78 | SLC6A2 (0.48) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL6435879 | 0.77 | MAPT (0.49) | L3MBTL1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL11632012 | 0.76 | L3MBTL1 (0.43) | L3MBTL1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL11632105 | 0.76 | ALDH1A1 (0.56) | L3MBTL1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL11625524 | 0.76 | GAA (0.48) | L3MBTL1SMN1; SMN2GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263791-A1 | STRUCTURAL ANALOGUES OF METHYLPHENIDATE AS PARKINSON'S DISEASE-MODIFYING AGENTS | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230263791-A1 | STRUCTURAL ANALOGUES OF METHYLPHENIDATE AS PARKINSON'S DISEASE-MODIFYING AGENTS | SNCA, PARK7, SYNJ1 | L3MBTL1 4474/4885SMN1; SMN2 134/4885GAA 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.