Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4219301 | 0.88 | OXTR (0.43) | OXTRAVPR1AGPR52HTTPPARG | |
| SCHEMBL4224567 | 0.87 | GPR52 (0.49) | OXTRAVPR1AGPR52PPARGPPARA | |
| SCHEMBL4226164 | 0.86 | TDP1 (0.43) | OXTRAVPR1AGPR52HTTLPAR1 | |
| SCHEMBL4224732 | 0.85 | OXTR (0.41) | OXTRAVPR1ALPAR1LPAR5ALDH1A1 | |
| SCHEMBL4226299 | 0.85 | OXTR (0.44) | OXTRAVPR1AGPR52LPAR1ALDH1A1 | |
| SCHEMBL4224856 | 0.84 | GPR52 (0.55) | OXTRAVPR1AGPR52HTTATM | |
| SCHEMBL4229060 | 0.84 | OXTR (0.39) | OXTRAVPR1APPARGLPAR1LPAR5 | |
| SCHEMBL4225092 | 0.83 | OXTR (0.48) | OXTRAVPR1AGPR52HTTPPARG | |
| SCHEMBL4596575 | 0.83 | TDP1 (0.42) | OXTRAVPR1AGPR52HTTLPAR1 | |
| SCHEMBL4226527 | 0.83 | OXTR (0.46) | OXTRAVPR1AGPR52LPAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261347-A1 | Dihydrobenzofuranyl alkanamine derivatives and methods for using same | WYETH (US) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261347-A1 | Dihydrobenzofuranyl alkanamine derivatives and methods for using same | ADRA2A, HTR2A, ADRA1A | OXTR 186/4885AVPR1A 28/4885GPR52 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.