Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372531 | 0.83 | HSD17B3 (0.62) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL30486066 | 0.83 | CA12 (0.61) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL18138409 | 0.83 | NQO1 (0.58) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL5459900 | 0.83 | CA12 (0.61) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL29046353 | 0.83 | NQO1 (0.50) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL29794226 | 0.83 | NQO1 (0.50) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL1209429 | 0.81 | PON1 (0.58) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL294208 | 0.81 | NQO1 (0.56) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL4211791 | 0.81 | NQO1 (0.61) | NQO1CA12CA1CA9CYP19A1 | |
| SCHEMBL28217721 | 0.81 | NQO1 (0.56) | NQO1CA12CA1CA9CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954761-A | Method for synthesizing 4-aldehyde-7-methylcoumarin by microwave-assisted method | 齐齐哈尔大学 | 2025-05-09 | — | — | CN | disclosed |
| CN-116925029-B | Coumarin-piperazine-dithiocarbamic acid ester hybrid, preparation method and application thereof | 宁夏大学 | 2025-01-28 | — | — | CN | disclosed |
| US-11970489-B1 | 4-[(substituted 1H-benzimidazol-2-ylsulfanyl)methyl]-6-substituted-2H-chromen-2-ones as larvicidal agents | King Faisal University (SA) | 2024-04-30 | — | — | US | disclosed |
| CN-116925029-A | Coumarin-piperazine-dithiocarbamic acid ester hybrid, preparation method and application thereof | 宁夏大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-110577559-B | Synthesis method of fluorosidase substrate for alpha-L-iduronidase determination | 江西科技师范大学 | 2023-02-17 | — | — | CN | disclosed |
| CN-112876837-B | Photoreduction degradation composition and preparation method and application thereof | 四川大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-112876837-A | Photoreduction degradation composition and preparation method and application thereof | 四川大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-111592634-B | Photoreduction self-degradation polymer and preparation method and application thereof | 四川大学 | 2021-04-09 | — | — | CN | disclosed |
| CN-111592634-A | Photoreduction self-degradation polymer and preparation method and application thereof | 四川大学 | 2020-08-28 | — | — | CN | disclosed |
| US-10202383-B2 | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-02-12 | — | — | US | disclosed |
| US-20020123032-A1 | Detection of disease related genes | THE TRUSTEES OF BOSTON UNIVERSITY | 2002-09-05 | — | — | US | disclosed |
| EP-1210449-A1 | METHODS FOR THE DETECTION, ANALYSIS AND ISOLATION OF NASCENT PROTEINS | Ambergen, Inc. (US) | 2002-06-05 | — | — | EP | disclosed |
| US-6358689-B1 | DETECTING NASCENT PROTEINS BY CREATING MISAMINOACYLATED TRNA WITH NON-RADIOACTIVE MARKERS; INTRODUCE MISAMINOACYLATED TRNA INTO TRANSLATION SYSTEM, INCORPORATING MARKER INTO NASCENT PROTEIN, PERFORM ELECTROPHORESIS TO DETECT MARKER | BOSTON UNIVERSITY | 2002-03-19 | — | — | US | disclosed |
| US-6344320-B1 | DETECTING A MARKER IN NACENT PROTEINS AND TRNA WITH AMINOACYLATION, EXPOSURE TO ELECTRIC FIELS | THE TRUSTEES OF BOSTON UNIVERSITY | 2002-02-05 | — | — | US | disclosed |
| US-6306628-B1 | PROVIDING TRNA MOLECULE CHARGED WITH AMINO ACID AND FLUOROPHORE MARKER, REACTING TRNA MOLECULE WITH MARKER TO CREATE TRNA/MARKER CONJUGATE WHEREIN AMINO ACID OF TRNA OF TRNA/MARKER CONJUGATE IS COVALENTLY BONDED TO MARKER | AMBERGEN, INCORPORATED | 2001-10-23 | — | — | US | disclosed |
| US-6303337-B1 | ADDING MISAMINOACYLATED INITIATOR TRNA THAT RECOGNIZES ONLY THE FIRST AUG CODON TO TRANSLATION SYSTEM; GENE EXPRESSION, EVALUATION; GENETIC ENGINEERING | AMBER GEN. INC. | 2001-10-16 | — | — | US | disclosed |
| US-6210941-B1 | KIT CONTAINING COMPONENT OF PROTEIN SYNTHESIS SYSTEM AND TRANSFER RNA MISAMINOACYLATED WITH DETECTABLE NONRADIOACTIVE MARKER; FOR LABELING PROTEINS AS THEY ARE PRODUCED | THE TRUSTEES OF BOSTON UNIVERSITY | 2001-04-03 | — | — | US | disclosed |
| WO-2001014578-A1 | METHODS FOR THE DETECTION, ANALYSIS AND ISOLATION OF NASCENT PROTEINS | AMBERGEN, INC. (US) | 2001-03-01 | — | — | WO | disclosed |
| US-5922858-A | MISAMINOACYLATED TRANSFER RIBONUCLEIC ACID WITH PHOTOCLEAVABLE MARKER; FOR INCORPORATION OF NON-RADIOACTIVE LABELS INTO NASCENT PROTEINS BY CELLULAR OR CELL-FREE TRANSLATION SYSTEMS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1999-07-13 | — | — | US | disclosed |
| US-5643722-A | MARKING PROTEINS AND DETECTION, INCUBATION | TRUSTEES OF BOSTON UNIVERSITY | 1997-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202383-B2 | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions | DPP8, DPP4, DPP3 | NQO1 752/4885CA12 2808/4885CA1 1472/4885 |
| US-11970489-B1 | 4-[(substituted 1H-benzimidazol-2-ylsulfanyl)methyl]-6-substituted-2H-chromen-2-ones as larvicidal agents | CASP2, CASP3, CASP8 | NQO1 637/4885CA12 4812/4885CA1 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.