SCHEMBL6374209

SCHEMBL6374209

C=CCN(CC=C)CCc1ccc(N=Nc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 5/20 0.48
OPRM1 P35372 4/20 0.48
OPRD1 P41143 4/20 0.48
BCHE P06276 8/20 0.46
SIGMAR1 Q99720 2/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
SLC6A2 P23975 1/20 0.42
HTR1D P28221 1/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HTR1E P28566 1/20 0.42
SLC6A4 P31645 1/20 0.42
ADRA1A P35348 1/20 0.42
HRH1 P35367 1/20 0.42
ADRA1B P35368 1/20 0.42
DRD3 P35462 1/20 0.42
HTR2B P41595 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3749579 0.84 OPRK1 (0.59) OPRK1OPRM1OPRD1BCHESIGMAR1
SCHEMBL6374448 0.83 ALDH1A1 (0.41) OPRK1OPRM1OPRD1BCHEKMT2A
Hydrochloric Acid SCHEMBL2831864 0.83 OPRK1 (0.60) OPRK1OPRM1OPRD1BCHESIGMAR1
Bromide SCHEMBL10656516 0.83 OPRK1 (0.57) OPRK1OPRM1OPRD1BCHESIGMAR1
SCHEMBL11573309 0.81 OPRK1 (0.64) OPRK1OPRM1OPRD1BCHESIGMAR1
SCHEMBL23280869 0.78 ALDH1A1 (0.46) KMT2AMEN1KDM4ESMN1; SMN2ALDH1A1
SCHEMBL6381502 0.74 KCNH2 (0.42) BCHESIGMAR1KMT2AMEN1KDM4E
SCHEMBL13278246 0.74 ALDH1A1 (0.63) KMT2AMEN1KDM4EALDH1A1TSHR
SCHEMBL13278248 0.74 ALDH1A1 (0.63) KMT2AMEN1KDM4EALDH1A1TSHR
SCHEMBL11496184 0.74 OPRK1 (0.50) OPRK1OPRM1OPRD1BCHESIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050101690-A1 Dye for an intraocular lens and an intraocular lens using it CANON-STAAR CO. INC. 2005-05-12 US claimed
US-20050101690-A1 Dye for an intraocular lens and an intraocular lens using it CANON-STAAR CO. INC. 2005-05-12 US disclosed
US-6878792-B2 Dye for an intraocular lens and an intraocular lens using it CANON-STAAR CO. INC. (JP) 2005-04-12 US disclosed
US-20030078359-A1 Dye for an intraocular lens and an intraocular lens using it CANON-STAAR CO. INC. 2003-04-24 US disclosed
EP-1293541-A2 Intraocular lens and dye therefor Canon-Staar Co., Inc. (JP) 2003-03-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050101690-A1 Dye for an intraocular lens and an intraocular lens using it IK, CRYAA, INCENP OPRK1 4726/4885OPRM1 4862/4885OPRD1 4717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.