Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14212007 | 0.88 | ALDH1A1 (0.55) | ALDH1A1POLBHTT | |
| SCHEMBL7840765 | 0.86 | PPARA (0.53) | HPGDP2RX3TAS1R3TAS1R1PPARA | |
| SCHEMBL15448867 | 0.84 | PPARA (0.43) | PPARAALDH1A1 | |
| SCHEMBL6374373 | 0.82 | PPARA (0.53) | HPGDPPARAALDH1A1POLB | |
| SCHEMBL11509018 | 0.80 | PTPRB (0.47) | — | |
| SCHEMBL11648125 | 0.79 | PTGS1 (0.44) | HPGDPPARAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL24042028 | 0.79 | PPARA (0.36) | HPGDP2RX3PPARAPOLBHTT | |
| SCHEMBL9917308 | 0.79 | CRHBP (0.47) | HPGDTAS1R3TAS1R1PPARAALDH1A1 | |
| SCHEMBL6720457 | 0.78 | BLM (0.57) | HPGDTAS1R3TAS1R1PPARAALDH1A1 | |
| SCHEMBL11530777 | 0.77 | HPGD (0.45) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843666-B1 | 4-SUBSTITUTED 5-POLYCYCLYLPYRIMIDINE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-05-16 | — | — | EP | disclosed |
| US-5780465-A | 4-substituted 5-polycyclylpyrimidine herbicides | DOW AGROSCIENCES LLC (US) | 1998-07-14 | — | — | US | disclosed |
| EP-0843666-A1 | 4-SUBSTITUTED 5-POLYCYCLYLPYRIMIDINE HERBICIDES | DOWELANCO (US) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997037978-A1 | 4-SUBSTITUTED 5-POLYCYCLYLPYRIMIDINE HERBICIDES | DOWELANCO (US) | 1997-10-16 | — | — | WO | disclosed |