SCHEMBL6374898

SCHEMBL6374898

CC1(C)c2cc(-c3cc(-c4ccccc4)nc(-c4ccccc4)c3)ccc2-c2ccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)ccc43)cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ ATM Q13315 1/20 0.38
▸ PTGER4 P35408 1/20 0.35
▸ ALDH1A1 P00352 4/20 0.33
▸ MAPT P10636 3/20 0.33
▸ MAPK1 P28482 2/20 0.33
▸ NPY5R Q15761 2/20 0.33
▸ HPGD P15428 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ TSPO P30536 1/20 0.32
▸ HDAC4 P56524 1/20 0.32
▸ ACACA Q13085 1/20 0.32
▸ PTGES O14684 1/20 0.32
▸ RXFP1 Q9HBX9 2/20 0.31
▸ RAC2 P15153 1/20 0.31
▸ RAC3 P60763 1/20 0.31
▸ CDC42 P60953 1/20 0.31
▸ RAC1 P63000 1/20 0.31
▸ KMT2A Q03164 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15197814 0.99 KDM4E (0.38) KDM4EL3MBTL1ATMPTGER4ALDH1A1
SCHEMBL19061253 0.93 PDK2 (0.37) KDM4EL3MBTL1ATMPTGER4ALDH1A1
SCHEMBL6372681 0.93 KDM4E (0.38) KDM4EL3MBTL1ATMPTGER4ALDH1A1
SCHEMBL14425629 0.92 KDM4E (0.35) KDM4EL3MBTL1ATMALDH1A1MAPT
SCHEMBL6375035 0.92 KDM4E (0.37) KDM4EL3MBTL1ATMPTGER4ALDH1A1
SCHEMBL8734503 0.92 KDM4E (0.37) KDM4EL3MBTL1ATMPTGER4NPY5R
SCHEMBL14212267 0.91 L3MBTL1 (0.44) KDM4EL3MBTL1ATMPTGER4ALDH1A1
SCHEMBL11981054 0.91 L3MBTL1 (0.46) KDM4EL3MBTL1ATMPTGER4ALDH1A1
SCHEMBL15248668 0.91 KDM4E (0.36) KDM4EL3MBTL1ATMPTGER4NPY5R
SCHEMBL19061212 0.91 PDK2 (0.36) KDM4EL3MBTL1ATMPTGER4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 — — US disclosed
US-10651398-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2020-05-12 — — US disclosed
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-01-29 — — US disclosed
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-01-17 — — US disclosed
US-20170229660-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-10 — — US disclosed
US-20170229660-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-10 — — US disclosed
US-9711732-B2 Organic electroluminescent element and material for organic electroluminescent elements IDEMITSU KOSAN CO., LTD. (JP) 2017-07-18 — — US disclosed
US-9711732-B2 Organic electroluminescent element and material for organic electroluminescent elements IDEMITSU KOSAN CO., LTD. (JP) 2017-07-18 — — US disclosed
US-9601708-B2 Organic light emitting device and materials for use in same UNIVERSAL DISPLAY CORPORATION (US) 2017-03-21 — — US disclosed
US-9601708-B2 Organic light emitting device and materials for use in same UNIVERSAL DISPLAY CORPORATION (US) 2017-03-21 — — US disclosed
US-8652654-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-02-18 — — US disclosed
US-20130306963-A1 ORGANIC LIGHT EMITTING DEVICE AND MATERIALS FOR USE IN SAME UNIVERSAL DISPLAY CORPORATION (US) 2013-11-21 — — US disclosed
US-20130234119-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2013-09-12 — — US disclosed
US-20130234119-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2013-09-12 — — US disclosed
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 — — US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 — — US disclosed
US-20120119197-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-05-17 — — US disclosed
US-20120119197-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-05-17 — — US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 — — US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, L1CAM, AGO2 KDM4E 3248/4885L3MBTL1 1678/4885ATM 2324/4885
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L KDM4E 984/4885L3MBTL1 1516/4885ATM 4547/4885
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same UQCRB, OXA1L, HBS1L KDM4E 984/4885L3MBTL1 1516/4885ATM 4547/4885
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element LEF1, L1CAM, AGO2 KDM4E 3248/4885L3MBTL1 1678/4885ATM 2324/4885
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same UQCRB, OXA1L, HBS1L KDM4E 984/4885L3MBTL1 1516/4885ATM 4547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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