SCHEMBL1002927

SCHEMBL1002927

O=C(O)C1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
RAB9A P51151 1/20 0.51
FABP5 Q01469 3/20 0.47
FABP7 O15540 2/20 0.47
ITGB3 P05106 1/20 0.46
ITGB1 P05556 1/20 0.46
ITGAV P06756 1/20 0.46
ITGA5 P08648 1/20 0.46
ITGA4 P13612 1/20 0.46
PREP P48147 3/20 0.45
F2 P00734 1/20 0.44
CTRB1 P17538 1/20 0.43
ACE P12821 2/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30564473 1.00 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2RAB9AFABP5FABP7
SCHEMBL29378245 1.00 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2RAB9AFABP5FABP7
SCHEMBL29503800 1.00 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2RAB9AFABP5FABP7
SCHEMBL29549607 1.00 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2RAB9AFABP5FABP7
SCHEMBL118354 1.00 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2RAB9AFABP5FABP7
SCHEMBL29349958 1.00 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2RAB9AFABP5FABP7
SCHEMBL29503770 1.00 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2RAB9AFABP5FABP7
SCHEMBL119560 1.00 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2RAB9AFABP5FABP7
Fluoride SCHEMBL7156757 0.99 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2RAB9AFABP5FABP7
Hydrochloric Acid SCHEMBL3669758 0.99 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2RAB9AFABP5FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4631955-A1 PURIFICATION METHOD AND PRODUCTION METHOD OF CYCLIC PEPTIDE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-10-15 EP disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-09 US disclosed
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-02 US disclosed
US-20250257094-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-14 US disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 US disclosed
US-20250230193-A1 CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-07-17 US disclosed
US-20250171494-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-05-29 US disclosed
US-12312379-B2 Methods for producing cyclic compounds comprising N-substituted amino acid residues CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-05-27 US disclosed
US-12281141-B2 Method for synthesizing peptide containing N-substituted amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-04-22 US disclosed
US-20090180958-A1 Diagnostic and therapeutic agents KARYON-CTT LTD. (FI) 2009-07-16 US disclosed
EP-2011800-A2 Inhibitors of caspase Vertex Pharmaceuticals Incorporated (US) 2009-01-07 EP disclosed
WO-2009000878-A1 KALLIKREIN 7 MODULATORS NOVARTIS AG (CH) 2008-12-31 WO disclosed
US-20080234202-A1 Non-natural amino acids and neurotensin analogues ARGOLYN BIOSCIENCES, INC. 2008-09-25 US disclosed
EP-1874800-A1 DIAGNOSTIC AND THERAPEUTIC AGENTS Karyon-CTT Ltd (FI) 2008-01-09 EP disclosed
WO-2006127948-A2 N-TERMINALLY MODIFIED GLP-1 RECEPTOR MODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2006-11-30 WO disclosed
WO-2006114478-A1 DIAGNOSTIC AND THERAPEUTIC AGENTS KARYON-CTT LTD (FI) 2006-11-02 WO disclosed
EP-1656390-A2 COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF MIGENIX INC. (CA) 2006-05-17 EP disclosed
US-20050153876-A1 Compositions of lipopeptide antibiotic derivatives and methods of use thereof MIGENIX INC. (CA) 2005-07-14 US disclosed
WO-2005000878-A2 COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF MIGENIX INC. (CA) 2005-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171494-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID NPPA, VIP, DNPEP ALDH1A1 4281/4885SMN1; SMN2 670/4885RAB9A 3414/4885
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS KRAS, HRAS, NRAS ALDH1A1 4331/4885SMN1; SMN2 4564/4885RAB9A 55/4885
US-12312379-B2 Methods for producing cyclic compounds comprising N-substituted amino acid residues NGLY1, NPPA, VIP ALDH1A1 4672/4885SMN1; SMN2 3569/4885RAB9A 3660/4885
US-20050153876-A1 Compositions of lipopeptide antibiotic derivatives and methods of use thereof NRDC, NOD2, NGLY1 ALDH1A1 4771/4885SMN1; SMN2 4461/4885RAB9A 3054/4885
US-20080234202-A1 Non-natural amino acids and neurotensin analogues NGLY1, NTSR1, NTSR2 ALDH1A1 4825/4885SMN1; SMN2 980/4885RAB9A 1757/4885
US-12281141-B2 Method for synthesizing peptide containing N-substituted amino acid NPPA, VIP, DNPEP ALDH1A1 4281/4885SMN1; SMN2 670/4885RAB9A 3414/4885
US-20090180958-A1 Diagnostic and therapeutic agents TPX2, ZFX, ZYX ALDH1A1 4820/4885SMN1; SMN2 4261/4885RAB9A 1646/4885
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid DNPEP, VIP, NPEPPS ALDH1A1 4328/4885SMN1; SMN2 2268/4885RAB9A 1443/4885
US-20250230193-A1 CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS KRAS, HRAS, NRAS ALDH1A1 4331/4885SMN1; SMN2 4564/4885RAB9A 55/4885
US-20250257094-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES NGLY1, NPPA, VIP ALDH1A1 4672/4885SMN1; SMN2 3569/4885RAB9A 3660/4885
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS ALDH1A1 4838/4885SMN1; SMN2 4201/4885RAB9A 65/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R ALDH1A1 4857/4885SMN1; SMN2 4620/4885RAB9A 3143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.