Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12397137 | 0.78 | LMNA (0.50) | OPRL1ALDH1A1AKR1C1OPRM1OPRD1 | |
| SCHEMBL25001486 | 0.77 | LPAR1 (0.38) | OPRL1CYP2C9 | |
| SCHEMBL28304679 | 0.76 | AKR1C1 (0.48) | OPRL1AKR1C1OPRM1OPRD1OPRK1 | |
| SCHEMBL12227090 | 0.72 | OPRM1 (0.61) | OPRL1OPRM1OPRD1OPRK1ADRA1A | |
| SCHEMBL501923 | 0.72 | AKR1C1 (0.57) | OPRL1AKR1C1OPRM1OPRD1OPRK1 | |
| SCHEMBL2722547 | 0.72 | AKR1C1 (0.57) | OPRL1AKR1C1OPRM1OPRD1OPRK1 | |
| SCHEMBL2158276 | 0.71 | HSD11B1 (0.46) | OPRL1ALDH1A1AKR1C1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL1804765 | 0.70 | AKR1C1 (0.55) | OPRL1AKR1C1OPRM1OPRD1OPRK1 | |
| SCHEMBL25001066 | 0.70 | LPAR1 (0.39) | OPRK1CYP2C9 | |
| SCHEMBL42114 | 0.69 | AKR1C1 (0.70) | OPRL1ALDH1A1AKR1C1HSD11B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203585-B1 | ANTI-ISCHEMIC AGENT | ZAKRYTOE AKTSIONERNOE OBSCHEST (RU) | 2005-03-16 | — | — | EP | disclosed |
| EP-1203585-A4 | ANTI-ISCHEMIC AGENT | ZAKRYTOE AKTSIONERNOE OBSCHEST (RU) | 2004-02-04 | — | — | EP | disclosed |
| WO-2001005399-A1 | ANTI-ISCHEMIC AGENT | ZAKRYTOE AKTSIONERNOE OBSCHESTVO 'ASGL-ISSLEDOVATELSKIE LABORATORII' (RU) | 2001-01-25 | — | — | WO | disclosed |