Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.57 |
| ▸ | TUBB | P07437 | 3/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7581752 | 0.87 | GLO1 (0.69) | ALDH1A1MAPTTUBB1TUBB4ATUBB | |
| SCHEMBL23270371 | 0.87 | ALDH1A1 (0.62) | ALDH1A1AOX1MAPTTUBB1TUBB4A | |
| SCHEMBL2213640 | 0.87 | MAPT (0.77) | ALDH1A1MAPTGAATDP1AKT1 | |
| SCHEMBL28552784 | 0.87 | MAPT (0.77) | ALDH1A1AOX1MAPTTUBB1TUBB4A | |
| SCHEMBL2225902 | 0.86 | GAA (0.75) | ALDH1A1MAPTGAATDP1CYP1A2 | |
| SCHEMBL6380063 | 0.85 | ALDH1A1 (0.60) | ALDH1A1AOX1MAPTTUBB1TUBB4A | |
| SCHEMBL31606907 | 0.84 | TUBB1 (0.67) | ALDH1A1AOX1MAPTTUBB1TUBB4A | |
| SCHEMBL7813363 | 0.83 | GAA (0.75) | ALDH1A1MAPTGAATDP1CYP1A2 | |
| SCHEMBL7813366 | 0.83 | GAA (0.75) | ALDH1A1MAPTGAATDP1CYP1A2 | |
| SCHEMBL11466495 | 0.82 | TUBB1 (0.48) | ALDH1A1AOX1MAPTTUBB1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032787-A1 | Pheny (alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity | SIGMA-TAU INDUSTRIES FARMACEUTICHE RIUNITE S.P.A. (IT) | 2005-02-10 | — | — | US | disclosed |
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | MITSUI CHEMICALS, INC. (JP) | 2003-11-13 | — | — | US | disclosed |
| EP-1266888-A1 | QUINOLINE DERIVATIVES AND MEDICINAL USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-4153713-A | NEUROPSYCHOTROPIC AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | PPARG, PPARD, PPARA | ALDH1A1 822/4885AOX1 1899/4885MAPT 2433/4885 |
| US-20050032787-A1 | Pheny (alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity | LIPC, CPT1A, GPR119 | ALDH1A1 1194/4885AOX1 2104/4885MAPT 3652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.