Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31193929 | 0.85 | KDM4E (0.55) | KDM4ENPSR1IDO1ALDH1A1MAPT | |
| SCHEMBL27838050 | 0.84 | KDM4E (0.50) | KDM4ENPSR1IDO1ALDH1A1MAPT | |
| SCHEMBL6377043 | 0.84 | KDM4E (0.59) | KDM4ENPSR1IDO1ALDH1A1MAPT | |
| SCHEMBL5077233 | 0.82 | KDM4E (0.58) | KDM4ENPSR1IDO1ALDH1A1MAPT | |
| SCHEMBL4192553 | 0.82 | KDM4E (0.58) | KDM4ENPSR1IDO1ALDH1A1MAPT | |
| SCHEMBL15567052 | 0.81 | KDM4E (0.64) | KDM4ENPSR1IDO1ALDH1A1MAPT | |
| SCHEMBL474055 | 0.81 | KDM4E (0.57) | KDM4ENPSR1IDO1ALDH1A1MAPT | |
| SCHEMBL19230697 | 0.81 | KDM4E (0.51) | KDM4ENPSR1IDO1ALDH1A1TSHR | |
| SCHEMBL22653500 | 0.81 | KDM4E (0.48) | KDM4ENPSR1IDO1ALDH1A1MAPT | |
| SCHEMBL30708516 | 0.81 | NNMT (0.47) | KDM4EALDH1A1NNMTTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114030-B1 | PYRIDINE KETONES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-01 | — | — | EP | disclosed |
| US-6498125-B2 | Pyridine ketones useful as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2002-12-24 | — | — | US | disclosed |
| US-20020016345-A1 | Pyridine ketones useful as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2002-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016345-A1 | Pyridine ketones useful as herbicides | DDT, PDHA1, IDH2 | KDM4E 461/4885NPSR1 2031/4885IDO1 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.