Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074737 | 0.89 | TAS1R3 (0.44) | MTNR1AMTNR1BLDHANPC1TP53 | |
| SCHEMBL7074193 | 0.87 | PPARG (0.56) | LDHAPPARGPPARAMAPTCYP1A2 | |
| SCHEMBL7073559 | 0.85 | PDE4B (0.48) | MTNR1AMTNR1BLDHANPC1ALDH1A1 | |
| SCHEMBL12264723 | 0.85 | MMP2 (0.49) | MTNR1AMTNR1BLDHANPC1TP53 | |
| SCHEMBL6377276 | 0.84 | PLA2G4B (0.41) | MTNR1AMTNR1BLDHANPC1ALDH1A1 | |
| SCHEMBL7075493 | 0.83 | ALDH1A1 (0.43) | MTNR1AMTNR1BLDHANPC1TP53 | |
| SCHEMBL7078743 | 0.82 | GRIK1 (0.48) | NPC1ALDH1A1RAB9APPARGPPARA | |
| SCHEMBL7075160 | 0.82 | MTNR1A (0.47) | MTNR1AMTNR1BLDHANPC1TP53 | |
| SCHEMBL6378034 | 0.80 | HTT (0.51) | MTNR1AMTNR1BALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL7077459 | 0.79 | MEN1 (0.46) | NPC1TP53ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929519-B1 | BETA-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | UPJOHN CO (US) | 2005-02-23 | — | — | EP | disclosed |
| CN-1158254-C | 'Beta'-sulfonyl hydroxamic acids as matrix metalloproteinases inhibitors | �������Ŷ���Լ��������˾ | 2004-07-21 | — | — | CN | disclosed |
| US-6235928-B1 | ENZYME INHIBITOR MATRIX METALLOPROTEINASE FAMILY, INCLUDING COLLAGENASE, STROMELYSIN, AND GELATINASE, THE COMPOUNDS OR PHARMACEUTICAL COMPOSITIONS | PHARMACIA & UPJOHN COMPANY | 2001-05-22 | — | — | US | disclosed |
| CN-1230177-A | 'Beta'-sulfonyl hydroxamic acids as matrix metalloproteinases inhibitors | UPJOHN CO (US) | 1999-09-29 | — | — | CN | disclosed |
| EP-0929519-A1 | $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-21 | — | — | EP | disclosed |
| US-5847153-A | β-sulfonyl hydroxamic acids | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1998013340-A1 | β-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-02 | — | — | WO | disclosed |