Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 5/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380946 | 0.86 | CYP19A1 (0.56) | PDE4DCYP19A1ACHE | |
| SCHEMBL6384704 | 0.83 | CYP19A1 (0.67) | PDE4DCYP19A1ACHE | |
| SCHEMBL1114939 | 0.81 | PDE4D (0.81) | PDE4DCYP19A1ACHE | |
| Hydrochloric Acid SCHEMBL2329428 | 0.80 | ACHE (0.71) | ACHE | |
| SCHEMBL6384672 | 0.80 | CYP19A1 (0.70) | PDE4DCYP19A1ACHE | |
| Bromide SCHEMBL2330791 | 0.78 | ACHE (0.73) | ACHE | |
| SCHEMBL7961218 | 0.77 | ACHE (0.62) | ACHEATM | |
| SCHEMBL6385559 | 0.74 | CYP19A1 (0.73) | PDE4DCYP19A1ACHE | |
| SCHEMBL6378133 | 0.72 | CYP19A1 (0.81) | PDE4DCYP19A1ACHE | |
| SCHEMBL6378154 | 0.72 | CYP19A1 (1.00) | PDE4DCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047674-B1 | PROCESS FOR PRODUCTION OF DONEPEZIL DERIVATIVES | EISAI CO LTD (JP) | 2005-03-30 | — | — | EP | disclosed |