Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | B3GNT2 | Q9NY97 | 2/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 4/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | PYGM | P11217 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL640777 | 0.82 | DAO (0.48) | PGRL3MBTL1B3GNT2 | |
| SCHEMBL641033 | 0.81 | DAO (0.45) | B3GNT2 | |
| SCHEMBL7183033 | 0.69 | MAPT (0.43) | PGRL3MBTL1TNKS | |
| SCHEMBL4241189 | 0.69 | LMNA (0.51) | PGRL3MBTL1 | |
| SCHEMBL639582 | 0.68 | PGR (0.42) | PGRFASNTDP2B3GNT2CYP19A1 | |
| SCHEMBL5794772 | 0.66 | POLB (0.47) | PGRL3MBTL1 | |
| SCHEMBL640386 | 0.66 | PGR (0.44) | PGRL3MBTL1FASNTDP2PYGL | |
| SCHEMBL20079379 | 0.66 | PGR (0.65) | PGRB3GNT2 | |
| SCHEMBL16883632 | 0.66 | CYP1A2 (0.55) | PGRB3GNT2 | |
| SCHEMBL638525 | 0.65 | PGR (0.38) | PGRL3MBTL1TDP2CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119676-B2 | Substituted benzimidazolone derivatives, medicaments comprising them and their use | Abbott GmbH & Co. HG (DE) | 2012-02-21 | — | — | US | disclosed |