Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | B3GNT2 | Q9NY97 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL640777 | 0.84 | DAO (0.48) | DAOKMT2AMEN1B3GNT2 | |
| SCHEMBL638524 | 0.81 | PGR (0.40) | B3GNT2 | |
| SCHEMBL1268409 | 0.78 | DAO (0.55) | DAOKMT2APOLBMEN1CYP1A2 | |
| SCHEMBL2310781 | 0.72 | DAO (0.46) | DAOKMT2APOLBMEN1CYP1A2 | |
| SCHEMBL4147944 | 0.71 | DAO (0.55) | DAOKMT2APOLBMEN1CYP1A2 | |
| SCHEMBL18948019 | 0.71 | CYP1A2 (0.60) | DAOKMT2APOLBMEN1CYP1A2 | |
| SCHEMBL7651882 | 0.69 | ADORA3 (0.54) | KMT2ACYP1A2 | |
| SCHEMBL640651 | 0.68 | POLB (0.59) | DAOKMT2APOLBMEN1CYP1A2 | |
| SCHEMBL27957535 | 0.67 | DAO (0.50) | DAOKMT2APOLBMEN1CYP1A2 | |
| SCHEMBL5266608 | 0.67 | DAO (0.50) | DAOKMT2APOLBMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119676-B2 | Substituted benzimidazolone derivatives, medicaments comprising them and their use | Abbott GmbH & Co. HG (DE) | 2012-02-21 | — | — | US | disclosed |