Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641033 | 0.84 | DAO (0.45) | DAOMEN1KMT2AB3GNT2 | |
| SCHEMBL638524 | 0.82 | PGR (0.40) | L3MBTL1PGRB3GNT2 | |
| SCHEMBL16997516 | 0.78 | DAO (0.60) | DAOMEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL7655193 | 0.70 | CA12 (0.58) | DAOMEN1LMNAKMT2AAURKA | |
| SCHEMBL8886284 | 0.70 | MEN1 (0.77) | DAOMEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL31743953 | 0.70 | MEN1 (0.77) | DAOMEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL640633 | 0.69 | B3GNT2 (0.54) | DAOMDM2PGRB3GNT2 | |
| SCHEMBL640146 | 0.68 | PPARG (0.45) | MEN1LMNAKMT2A | |
| SCHEMBL7652823 | 0.68 | CA9 (0.58) | MEN1LMNAKMT2AL3MBTL1CA12 | |
| SCHEMBL319785 | 0.67 | DAO (0.52) | DAOADORA3GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119676-B2 | Substituted benzimidazolone derivatives, medicaments comprising them and their use | Abbott GmbH & Co. HG (DE) | 2012-02-21 | — | — | US | disclosed |