Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280884 | 0.90 | BCHE (0.46) | ABCG2TNFRSF1ABCHEACHEPTPN1 | |
| SCHEMBL4849986 | 0.90 | BCHE (0.46) | ABCG2TNFRSF1ABCHEACHEPTPN1 | |
| SCHEMBL4852218 | 0.90 | CAPN1 (0.50) | TNFRSF1ABCHEACHEMAPTLMNA | |
| SCHEMBL4849921 | 0.89 | BCHE (0.45) | TNFRSF1ABCHEACHEMAPTKDM4E | |
| SCHEMBL4856242 | 0.89 | BCHE (0.45) | ABCG2TNFRSF1ABCHEACHEMAPT | |
| SCHEMBL4849165 | 0.89 | BCHE (0.58) | ABCG2TNFRSF1ABCHEACHEMAPT | |
| SCHEMBL4853736 | 0.89 | BCHE (0.52) | TNFRSF1ABCHEACHEMAPTKDM4E | |
| SCHEMBL4847755 | 0.87 | TNFRSF1A (0.46) | ABCG2TNFRSF1APTPN1 | |
| SCHEMBL4847433 | 0.87 | TNFRSF1A (0.46) | ABCG2TNFRSF1ADPP4PTPN1ALDH1A1 | |
| SCHEMBL4846635 | 0.86 | LMNA (0.48) | ABCG2TNFRSF1AMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050227990-A1 | Aminoalkoxy-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2005-10-13 | — | — | US | claimed |