SCHEMBL6387886

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29186383	0.91	RAF1 (0.49)	KDRRAF1EPHX2BRAFDDR2
	SCHEMBL29186375	0.90	KDR (0.47)	KDRRAF1EPHX2BRAFDDR2
	SCHEMBL6478594	0.89	GCK (0.51)	KDRRAF1EPHX2BRAFHIPK4
	SCHEMBL6427439	0.88	KDR (0.50)	KDRRAF1EPHX2BRAFDDR2
	SCHEMBL29130657	0.85	KDR (0.53)	KDRRAF1EPHX2BRAFDDR2
	SCHEMBL1137279	0.85	MET (0.42)	KDRRAF1BRAFAXLGCK
	SCHEMBL30306976	0.83	KDR (0.54)	KDRRAF1EPHX2BRAFHIPK4
	SCHEMBL12355376	0.83	KDR (0.50)	KDRRAF1EPHX2BRAFDDR2
	SCHEMBL2029492	0.83	KDR (0.54)	KDRRAF1EPHX2BRAFHIPK4
	SCHEMBL6426864	0.83	KDR (0.50)	KDRRAF1EPHX2BRAFDDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.