Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077880 | 0.95 | KMT2A (0.55) | KMT2ACTNNB1WNT3AHDAC1HDAC8 | |
| SCHEMBL25456558 | 0.93 | KMT2A (0.53) | KMT2ACTNNB1WNT3AHDAC1HDAC8 | |
| SCHEMBL7865396 | 0.90 | KMT2A (0.58) | KMT2ACTNNB1WNT3AMMP2MMP9 | |
| SCHEMBL10986985 | 0.87 | HDAC1 (0.63) | KMT2AHDAC1HDAC8ALDH1A1MAPT | |
| SCHEMBL8535748 | 0.84 | KMT2A (0.63) | KMT2ACTNNB1WNT3AALDH1A1POLB | |
| SCHEMBL6138894 | 0.83 | ALDH1A1 (0.50) | KMT2AHDAC1HDAC8ALDH1A1NPC1 | |
| SCHEMBL6138736 | 0.83 | HAO1 (0.56) | HDAC1HDAC8MMP2MMP9MMP8 | |
| SCHEMBL9419411 | 0.82 | KMT2A (0.69) | KMT2ACTNNB1WNT3AALDH1A1MAPT | |
| SCHEMBL9077833 | 0.81 | HSD17B3 (0.66) | HDAC1HDAC8ALDH1A1POLBNPC1 | |
| SCHEMBL6138742 | 0.81 | CSF1R (0.43) | CTNNB1WNT3AHDAC1HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119305-A1 | Il-6 production inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119305-A1 | Il-6 production inhibitors | IL6, IL6ST, PADI6 | KMT2A 829/4885CTNNB1 1722/4885WNT3A 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.