Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18685663 | 0.76 | ALOX5 (0.65) | ALDH1A1ALOX5EPHX1TSHRTHRB | |
| SCHEMBL18657390 | 0.76 | ALOX5 (0.65) | ALDH1A1ALOX5EPHX1TSHRTHRB | |
| SCHEMBL29971764 | 0.76 | ALOX5 (0.65) | ALDH1A1ALOX5EPHX1TSHRTHRB | |
| SCHEMBL11659426 | 0.76 | EPHX1 (0.52) | ALDH1A1ALOX5EPHX1TSHRTHRB | |
| SCHEMBL11662768 | 0.76 | EPHX1 (0.52) | ALDH1A1ALOX5EPHX1TSHRTHRB | |
| SCHEMBL6400658 | 0.73 | CYP1A2 (0.39) | ALDH1A1ALOX5EPHX1TSHRTHRB | |
| SCHEMBL10486372 | 0.73 | EPHX1 (0.48) | ALDH1A1ALOX5EPHX1TSHRTHRB | |
| SCHEMBL726033 | 0.73 | ALOX5 (0.61) | ALDH1A1ALOX5EPHX1TSHRTHRB | |
| SCHEMBL1573174 | 0.72 | ALOX5 (0.50) | ALDH1A1ALOX5EPHX1TSHRTHRB | |
| SCHEMBL1437889 | 0.72 | ALOX5 (0.50) | ALDH1A1ALOX5EPHX1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494005-B1 | Multicomponent agent or kit for the preparation of the sulphoconjugated forms of pyridino-, pyrimidino- or triazino-N-oxyde compounds and method of application thereof | OREAL (FR) | 1997-02-05 | — | — | EP | claimed |
| US-5360804-A | STABILITY | L'OREAL (FR) | 1994-11-01 | — | — | US | claimed |
| EP-1406911-B1 | 6-[2-(PHOSPHONOMETHOXY)ALKOXY] PYRIMIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 2016-01-06 | — | — | EP | disclosed |
| US-20050049232-A1 | Composition | LINDAU PAR (SE) | 2005-03-03 | — | — | US | disclosed |
| US-20050038058-A1 | Novel compounds and methods for therapy | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY | 2005-02-17 | — | — | US | disclosed |
| US-6818633-B2 | Antiviral for RNA or DNA viruses such as HIV, HBV or HSV; acyclic pyrimidine nucleoside phosphonate analogues; 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidine; ; alkylating the 6-hydroxypyrimidine base with a dialkyl 2-chloroethoxymethylphosphonate | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2004-11-16 | — | — | US | disclosed |
| EP-1463483-A1 | NEW COMPOSITION | Ponsus Pharma AB (SE) | 2004-10-06 | — | — | EP | disclosed |
| EP-1406911-A1 | 6-[2-(PHOSPHONOMETHOXY)ALKOXY]PYRIMIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003055454-A1 | NEW COMPOSITION | PONSUS PHARMA AB (SE) | 2003-07-10 | — | — | WO | disclosed |
| US-20030109499-A1 | Novel compounds and methods for therapy | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ACADEMY OF SCIENCES | 2003-06-12 | — | — | US | disclosed |
| WO-2003002580-A1 | 6-`2-(PHOSPHONOMETHOXY)ALKOXY PYRIMIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OFTHE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2003-01-09 | — | — | WO | disclosed |
| EP-0187854-A1 | SUBSTITUTED PYRIMIDINE OXIDES USEFUL FOR HAIR GROWTH PROMOTION | BAZZANO, Gail S (US) | 1986-07-23 | — | — | EP | disclosed |
| WO-1986000616-A1 | SUBSTITUTED PYRIMIDINE OXIDES USEFUL FOR HAIR GROWTH PROMOTION | BAZZANO GAIL SANSONE | 1986-01-30 | — | — | WO | disclosed |
| US-4393065-A | INCREASED PRODUCTIVITY OF BY-PRODUCTS BY INCLUSION OF PYRIMIDINE COMPOUNDS | THE UPJOHN COMPANY (US) | 1983-07-12 | — | — | US | disclosed |
| US-4316901-A | Animal feed and process | THE UPJOHN COMPANY (US) | 1982-02-23 | — | — | US | disclosed |
| US-4315930-A | A DIAMINO-TRIAZINE-3-OXIDE | THE UPJOHN COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| EP-0042669-A2 | Compounds and compositions for use in animal feeds | THE UPJOHN COMPANY (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4308271-A | PYRIMIDINE OXIDE DERIVATIVES TO INCREASE PRODUCTION | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4307093-A | INCREASING PRODUCTION USING OXATRIAZINES | THE UPJOHN COMPANY (US) | 1981-12-22 | — | — | US | disclosed |
| US-4282228-A | Animal feed and process | THE UPJOHN COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038058-A1 | Novel compounds and methods for therapy | ZC3HAV1, IFNAR1, EIF2AK2 | ALDH1A1 2417/4885ALOX5 4337/4885EPHX1 1245/4885 |
| US-20050049232-A1 | Composition | CUTA, LIPG, LIPA | ALDH1A1 1751/4885ALOX5 165/4885EPHX1 1787/4885 |
| US-20030109499-A1 | Novel compounds and methods for therapy | IFNAR1, ZC3HAV1, EIF2AK2 | ALDH1A1 1605/4885ALOX5 4303/4885EPHX1 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.