Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.59 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17392707 | 1.00 | NOTUM (0.59) | NOTUMMBTD1L3MBTL3L3MBTL1AR | |
| SCHEMBL3436548 | 1.00 | NOTUM (0.59) | NOTUMMBTD1L3MBTL3L3MBTL1AR | |
| SCHEMBL16292723 | 0.89 | NOTUM (0.54) | NOTUMMBTD1L3MBTL3L3MBTL1AR | |
| SCHEMBL6628944 | 0.88 | ALDH1A1 (0.53) | NOTUMMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL3537362 | 0.87 | MBTD1 (0.57) | NOTUMMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| Trifluoroacetic Acid SCHEMBL4748972 | 0.87 | NOTUM (0.55) | NOTUMRORCDPP4 | |
| Hydrochloric Acid SCHEMBL28187302 | 0.86 | ALDH1A1 (0.51) | NOTUMMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| Water SCHEMBL27700656 | 0.86 | ALDH1A1 (0.51) | NOTUMMBTD1L3MBTL3L3MBTL1AR | |
| Hydrochloric Acid SCHEMBL1920820 | 0.85 | MBTD1 (0.55) | NOTUMMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL28940844 | 0.85 | MBTD1 (0.55) | NOTUMMBTD1L3MBTL3L3MBTL1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270748-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2024-08-15 | — | — | US | claimed |
| US-20050267156-A1 | Broadspectrum 2-amino-benzothiazole sulfonamide hiv protease inhibitors | TIBOTEC PHARMACEUTICALS LTD. | 2005-12-01 | — | — | US | claimed |
| US-20240270748-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2024-08-15 | — | — | US | disclosed |
| US-20240018125-A1 | CYCLIC ISOTHIOUREA DERIVATIVES AS CXCR4 MODULATORS | ERMIUM THERAPEUTICS (FR) | 2024-01-18 | — | — | US | disclosed |
| CN-116568675-A | Cyclic isothiourea derivatives as CXCR4 modulators | 埃尔米乌治疗公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-4217353-A1 | CYCLIC ISOTHIOUREA DERIVATIVES AS CXCR4 MODULATORS | Ermium Therapeutics (FR) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022064075-A1 | CYCLIC ISOTHIOUREA DERIVATIVES AS CXCR4 MODULATORS | ERMIUM THERAPEUTICS (FR) | 2022-03-31 | — | — | WO | disclosed |
| US-9745328-B2 | Flap modulators | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-29 | — | — | US | disclosed |
| US-9580416-B2 | Inhibitors of Bruton's tyrosine kinase | PHARMACYCLICS LLC (US) | 2017-02-28 | — | — | US | disclosed |
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| EP-3049405-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | Pharmakea Inc. (US) | 2016-08-03 | — | — | EP | disclosed |
| US-6130338-A | OXIDATING THE CORRESPONDING 3-PYRROLINE COMPOUND TO GIVE AN EPOXYPYRROLIDINE COMPOUND | TORAY INDUSTRIES, INC. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0974602-A1 | Catalyst and process for hydrogenating olefinically unsaturated compound | JSR Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |
| EP-0826687-A1 | Carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0774465-A1 | Penem derivatives and antimicrobial agents containing the same | SUNTORY LIMITED (JP) | 1997-05-21 | — | — | EP | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
| EP-0513247-A4 | SIDE CHAIN COPOLYMERS EXHIBITING NONLINEAR OPTICAL RESPONSE | — | 1993-02-03 | — | — | EP | disclosed |
| EP-0513247-A1 | SIDE CHAIN COPOLYMERS EXHIBITING NONLINEAR OPTICAL RESPONSE | HOECHST CELANESE CORPORATION (US) | 1992-11-19 | — | — | EP | disclosed |
| WO-1991012462-A1 | SIDE CHAIN COPOLYMERS EXHIBITING NONLINEAR OPTICAL RESPONSE | HOECHST CELANESE CORPORATION (US) | 1991-08-22 | — | — | WO | disclosed |
| US-5041509-A | Side chain copolymers exhibiting nonlinear optical response | CORNING INCORPORATRED | 1991-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270748-A1 | TRICYCLIC HETEROCYCLES | YAP1, TERF2IP, TEAD1 | NOTUM 4164/4885MBTD1 521/4885L3MBTL3 1580/4885 |
| US-20240018125-A1 | CYCLIC ISOTHIOUREA DERIVATIVES AS CXCR4 MODULATORS | CXCR4, CXCR1, CXCL12 | NOTUM 4743/4885MBTD1 966/4885L3MBTL3 4797/4885 |
| US-20050267156-A1 | Broadspectrum 2-amino-benzothiazole sulfonamide hiv protease inhibitors | PRSS1, SPINT2, TMPRSS2 | NOTUM 919/4885MBTD1 194/4885L3MBTL3 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.