Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798236 | 0.82 | GRM5 (0.55) | ALDH1A1GRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6797207 | 0.80 | GRM5 (0.52) | ALDH1A1GRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6429370 | 0.79 | NR3C2 (0.53) | ALDH1A1GRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6395028 | 0.76 | GRM5 (0.50) | ALDH1A1GRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6393511 | 0.72 | GRM5 (0.44) | ALDH1A1GRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7266673 | 0.72 | GRM5 (0.49) | ALDH1A1GRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6392419 | 0.71 | RIPK1 (0.41) | ALDH1A1GRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23076327 | 0.71 | RIPK1 (0.48) | ALDH1A1GRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2599678 | 0.71 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTHSD17B10GRM5 | |
| SCHEMBL30514060 | 0.71 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTHSD17B10GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165011-A1 | Benzoxazine and benzoxazinone substituted triazoles | GELLIBERT FRANCOISE J (FR) | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165011-A1 | Benzoxazine and benzoxazinone substituted triazoles | ACVR1, TGFBR1, SMAD3 | ALDH1A1 3541/4885GAA 1537/4885MAPT 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.