Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.53 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 4/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400025 | 0.81 | NR3C2 (0.55) | NR3C2MMP12PARP1SMN1; SMN2RAB9A | |
| SCHEMBL6394244 | 0.80 | NR3C2 (0.58) | NR3C2MMP12PARP1SMN1; SMN2RAB9A | |
| SCHEMBL6398786 | 0.79 | ALDH1A1 (0.49) | GRM5SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL6621422 | 0.78 | NR3C2 (0.52) | NR3C2MMP12GRM5PARP1SMN1; SMN2 | |
| SCHEMBL6321386 | 0.77 | NR3C2 (0.58) | NR3C2MMP12GRM5PARP1SMN1; SMN2 | |
| SCHEMBL4710570 | 0.76 | GRM5 (0.48) | MMP12GRM5SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6178668 | 0.76 | RIPK1 (0.47) | GRM5SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL6798236 | 0.75 | GRM5 (0.55) | GRM5SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL6391869 | 0.73 | HTR1A (0.47) | GRM5SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL6797207 | 0.73 | GRM5 (0.52) | GRM5SMN1; SMN2RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165011-A1 | Benzoxazine and benzoxazinone substituted triazoles | GELLIBERT FRANCOISE J (FR) | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165011-A1 | Benzoxazine and benzoxazinone substituted triazoles | ACVR1, TGFBR1, SMAD3 | NR3C2 988/4885MMP12 1888/4885GRM5 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.