Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | CDYL2 | Q8N8U2 | 5/20 | 0.54 |
| ▸ | CDYL | Q9Y232 | 5/20 | 0.54 |
| ▸ | CBX7 | O95931 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722012 | 0.88 | GRIN2B (0.52) | GRIN2BNPC1RAB9ASMN1; SMN2KMT2A | |
| Bromide SCHEMBL6074281 | 0.85 | NPC1 (0.49) | ALDH1A1GRIN2BNPC1RAB9ACDYL2 | |
| SCHEMBL10531109 | 0.85 | MAPT (0.51) | ALDH1A1GRIN2BNPC1RAB9ACDYL2 | |
| SCHEMBL6401176 | 0.84 | GRIN2B (0.55) | GRIN2BNPC1SMN1; SMN2KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL10528594 | 0.84 | MAPT (0.50) | ALDH1A1GRIN2BNPC1RAB9ACDYL2 | |
| Bromide SCHEMBL3853590 | 0.84 | NPC1 (0.53) | ALDH1A1GRIN2BNPC1RAB9ACDYL2 | |
| Iodide SCHEMBL10531088 | 0.84 | MAPT (0.50) | ALDH1A1GRIN2BNPC1RAB9ACDYL2 | |
| Bromide SCHEMBL10526720 | 0.84 | NPC1 (0.53) | ALDH1A1GRIN2BNPC1RAB9ACDYL2 | |
| SCHEMBL6399172 | 0.84 | RAB9A (0.58) | ALDH1A1GRIN2BNPC1RAB9ACDYL2 | |
| SCHEMBL29794014 | 0.81 | CDYL2 (0.46) | ALDH1A1GRIN2BNPC1RAB9ACDYL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | SMITHKLINE BEECHAM CORPORATION | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | CXCR3, CXCR1, CCR7 | ALDH1A1 1784/4885GRIN2B 1128/4885NPC1 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.