Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CDYL2 | Q8N8U2 | 4/20 | 0.55 |
| ▸ | CDYL | Q9Y232 | 4/20 | 0.55 |
| ▸ | CBX7 | O95931 | 2/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722009 | 0.88 | CES2 (0.52) | RAB9ANPC1GRIN2BKMT2ASMN1; SMN2 | |
| SCHEMBL10531119 | 0.84 | SMN1; SMN2 (0.52) | RAB9ANPC1CDYL2CDYLCBX7 | |
| SCHEMBL6401174 | 0.84 | GRIN2B (0.50) | RAB9ANPC1GRIN2BKMT2AKDM4E | |
| SCHEMBL6399178 | 0.84 | ALDH1A1 (0.60) | RAB9ANPC1ALDH1A1CDYL2CDYL | |
| SCHEMBL6399971 | 0.80 | HTT (0.46) | RAB9ANPC1GRIN2BKMT2ASMN1; SMN2 | |
| SCHEMBL6404557 | 0.78 | MGAM (0.43) | RAB9ANPC1ALDH1A1GRIN2BKMT2A | |
| SCHEMBL9520003 | 0.77 | RAB9A (0.74) | RAB9ANPC1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL10528536 | 0.75 | CDYL2 (0.49) | RAB9ANPC1ALDH1A1CDYL2CDYL | |
| SCHEMBL6399164 | 0.75 | KMT2A (0.57) | RAB9ANPC1ALDH1A1CDYL2CDYL | |
| SCHEMBL6399169 | 0.75 | KMT2A (0.57) | RAB9ANPC1ALDH1A1CDYL2CDYL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | SMITHKLINE BEECHAM CORPORATION | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | CXCR3, CXCR1, CCR7 | RAB9A 2446/4885NPC1 1098/4885ALDH1A1 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.