Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 6/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5996436 | 0.95 | RXRB (0.37) | POLBRXRBGABRA1GABRB2HTR1D | |
| SCHEMBL2499311 | 0.86 | KDM4E (0.41) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL6399268 | 0.84 | CYP3A4 (0.40) | MEN1KMT2ATSHRHPGD | |
| SCHEMBL5997923 | 0.79 | L3MBTL1 (0.36) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL152305 | 0.78 | TDP1 (0.37) | GABRA1GABRB2ALDH1A1HPGDRAB9A | |
| SCHEMBL5994813 | 0.75 | ALDH1A1 (0.36) | POLBMEN1KMT2AALDH1A1ACHE | |
| SCHEMBL5996314 | 0.74 | MEN1 (0.40) | POLBMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL5996157 | 0.73 | KDM4E (0.38) | POLBGABRA1GABRB2MEN1KMT2A | |
| SCHEMBL501929 | 0.73 | POLB (0.44) | POLBRXRBGABRA1GABRB2HTR1D | |
| SCHEMBL112083 | 0.73 | POLB (0.44) | POLBRXRBGABRA1GABRB2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969733-B2 | Photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-11-29 | — | — | US | disclosed |
| US-20030139485-A1 | Photoinitiators | WOLF JEAN-PIERRE (CH) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139485-A1 | Photoinitiators | DHCR24, NR1I3, CBR1 | POLB 1422/4885RXRB 550/4885GABRA1 2372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.