Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.65 |
| ▸ | DRD4 | P21917 | 1/20 | 0.65 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025525 | 0.94 | DRD2 (0.58) | DRD2DRD4GRM2SMN1; SMN2KMT2A | |
| SCHEMBL7533466 | 0.92 | DRD2 (0.60) | DRD2DRD4GRM2SMN1; SMN2KMT2A | |
| SCHEMBL14463703 | 0.92 | DRD2 (0.63) | DRD2DRD4GRM2SMN1; SMN2KMT2A | |
| SCHEMBL7999797 | 0.87 | DRD2 (0.54) | DRD2DRD4GRM2SMN1; SMN2KMT2A | |
| SCHEMBL14464365 | 0.86 | DRD2 (0.65) | DRD2DRD4GRM2SMN1; SMN2KMT2A | |
| SCHEMBL31145168 | 0.85 | DRD2 (0.58) | DRD2DRD4GRM2SMN1; SMN2KMT2A | |
| SCHEMBL144856 | 0.84 | DRD2 (0.52) | DRD2DRD4GRM2SMN1; SMN2KMT2A | |
| SCHEMBL13202810 | 0.84 | KMT2A (0.63) | DRD2DRD4GRM2SMN1; SMN2KMT2A | |
| SCHEMBL904827 | 0.83 | LMNA (0.55) | DRD2DRD4GRM2SMN1; SMN2KMT2A | |
| SCHEMBL7503033 | 0.82 | SMN1; SMN2 (0.61) | DRD2DRD4GRM2SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130961-A1 | Muscarinic M1 receptor agonists for pain management | ACADIA PHARMACEUTICALS INC. | 2005-06-16 | — | — | US | disclosed |
| US-20050075372-A1 | Method for controlling particular insect pest by applying anthranilamide compounds | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130961-A1 | Muscarinic M1 receptor agonists for pain management | CHRM1, CHRM3, CHRM2 | DRD2 346/4885DRD4 609/4885GRM2 59/4885 |
| US-20050075372-A1 | Method for controlling particular insect pest by applying anthranilamide compounds | ANTXR2, HRH4, HDAC10 | DRD2 3786/4885DRD4 3046/4885GRM2 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.