Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399328 | 0.94 | DRD2 (0.65) | DRD2DRD4GRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7533466 | 0.86 | DRD2 (0.60) | DRD2DRD4GRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL14463703 | 0.86 | DRD2 (0.63) | DRD2DRD4GRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7999797 | 0.81 | DRD2 (0.54) | DRD2DRD4GRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL14464365 | 0.80 | DRD2 (0.65) | DRD2DRD4GRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL31145168 | 0.80 | DRD2 (0.58) | DRD2DRD4GRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL144856 | 0.78 | DRD2 (0.52) | DRD2DRD4GRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL13202810 | 0.78 | KMT2A (0.63) | DRD2DRD4GRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL904827 | 0.78 | LMNA (0.55) | DRD2DRD4GRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7503033 | 0.77 | SMN1; SMN2 (0.61) | DRD2DRD4GRM2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | claimed |