Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28554314 | 0.74 | DAO (0.49) | CA12DAOMAPTHTTTDP1 | |
| SCHEMBL11865299 | 0.74 | HDAC1 (0.59) | CA12HDAC1DAOMAPTHTT | |
| SCHEMBL1237529 | 0.73 | MTNR1A (0.50) | HDAC1DAOACHETSHRKMT2A | |
| SCHEMBL7635264 | 0.72 | PIM1 (0.64) | CA12HDAC1DAOMAPTHTT | |
| SCHEMBL1239220 | 0.72 | L3MBTL1 (0.56) | HDAC1ACHETSHRHCRTR1HCRTR2 | |
| SCHEMBL1337353 | 0.71 | CA12 (0.57) | CA12DAOMAPTHTTALDH1A1 | |
| SCHEMBL1239185 | 0.71 | L3MBTL1 (0.59) | MAPTHTTACHETSHRALDH1A1 | |
| SCHEMBL1240094 | 0.71 | DAO (0.43) | CA12HDAC1DAOMAPTHTT | |
| SCHEMBL13952097 | 0.70 | PARP1 (0.40) | CA12HDAC1ACP3 | |
| SCHEMBL8128225 | 0.70 | DAO (0.48) | CA12HDAC1DAOMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| US-6936633-B2 | Pyrrolidinone derivatives | UCB S.A. (BE) | 2005-08-30 | — | — | US | disclosed |
| US-20050004180-A1 | Pyrrolidinone derivatives | USB S.A. (BE) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004180-A1 | Pyrrolidinone derivatives | CCR2, CCR1, CCL2 | CA12 4633/4885HDAC1 192/4885DAO 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.