Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914403 | 0.84 | L3MBTL1 (0.38) | L3MBTL1GABRA1GABRB2GRIN2DGRIN3B | |
| SCHEMBL29148797 | 0.80 | GABRA1 (0.46) | L3MBTL1GABRA1GABRB2GRIN2DGRIN3B | |
| SCHEMBL3958491 | 0.80 | L3MBTL1 (0.57) | L3MBTL1GABRA1GABRB2GRIN2DGRIN3B | |
| SCHEMBL9764653 | 0.80 | L3MBTL1 (0.57) | L3MBTL1GABRA1GABRB2GRIN2DGRIN3B | |
| SCHEMBL2737240 | 0.78 | L3MBTL1 (0.55) | L3MBTL1GABRA1GABRB2GRIN2DGRIN3B | |
| SCHEMBL3217546 | 0.76 | L3MBTL1 (0.53) | L3MBTL1GABRA1GABRB2GRIN2DGRIN3B | |
| SCHEMBL18991348 | 0.76 | L3MBTL1 (0.53) | L3MBTL1GABRA1GABRB2GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL2860733 | 0.76 | L3MBTL1 (0.53) | L3MBTL1GABRA1GABRB2GRIN2DGRIN3B | |
| SCHEMBL20743821 | 0.76 | L3MBTL1 (0.53) | L3MBTL1GABRA1GABRB2GRIN2DGRIN3B | |
| SCHEMBL892805 | 0.76 | L3MBTL1 (0.53) | L3MBTL1GABRA1GABRB2GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953866-B2 | Process for preparing ortho substituted phenylamines | CROMPTON CORPORATION (US) | 2005-10-11 | — | — | US | disclosed |
| WO-2004072028-A2 | PROCESS FOR PREPARING ORTHO SUBSTITUTED PHENYLAMINES | CROMPTON CORPORATION (US) | 2004-08-26 | — | — | WO | disclosed |
| US-20040162444-A1 | Process for preparing ortho substituted phenylamines | ADDIVANT USA, LLC | 2004-08-19 | — | — | US | disclosed |
| US-5689007-A | REACTING PHENYLHYDROXYAMINE WITH A NUCLEOPHILIC REAGENT INPRESENCE OF A HOMOGENEOUS ACID CATALYST | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-11-18 | — | — | US | disclosed |
| US-5574187-A | Process of preparing para substituted phenylamines | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1996-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162444-A1 | Process for preparing ortho substituted phenylamines | PNMT, TYR, COMT | L3MBTL1 2512/4885GABRA1 4348/4885GABRB2 4425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.