SCHEMBL892805

SCHEMBL892805

CC(C)Nc1ccccc1C(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.53
POLB P06746 1/20 0.48
TDP1 Q9NUW8 2/20 0.46
GABRA1 P14867 3/20 0.44
GABRB2 P47870 2/20 0.44
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
GRIN3A Q8TCU5 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
IDO1 P14902 1/20 0.44
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
LMNA P02545 2/20 0.41
CYP3A4 P08684 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9818623 0.90 TDP1 (0.65) L3MBTL1POLBTDP1GABRA1GABRB2
SCHEMBL11780688 0.82 IDO1 (0.46) L3MBTL1POLBTDP1GABRA1GABRB2
SCHEMBL2962223 0.82 TDP1 (0.57) L3MBTL1TDP1IDO1MAPTLMNA
SCHEMBL3958491 0.80 L3MBTL1 (0.57) L3MBTL1POLBGABRA1GABRB2GRIN2D
SCHEMBL9764653 0.80 L3MBTL1 (0.57) L3MBTL1POLBGABRA1GABRB2GRIN2D
SCHEMBL28698381 0.79 L3MBTL1 (0.47) L3MBTL1POLBGABRA1GABRB2GRIN2D
SCHEMBL2737240 0.78 L3MBTL1 (0.55) L3MBTL1POLBTDP1GABRA1GABRB2
SCHEMBL27591069 0.77 L3MBTL1 (0.50) L3MBTL1POLBGABRA1GABRB2GRIN2D
SCHEMBL3217546 0.76 L3MBTL1 (0.53) L3MBTL1POLBGABRA1GABRB2GRIN2D
SCHEMBL18991348 0.76 L3MBTL1 (0.53) L3MBTL1POLBGABRA1GABRB2GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399322-A1 EIF4E INHIBITORS AND USES THEREOF PIC Therapeutics, Inc. 2023-12-14 US disclosed
WO-2022183008-A9 AMINO-BENZIMIDAZOLE CATALYSTS FOR THE PREPARATION OF POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-12 WO disclosed
US-11753403-B2 EIF4E inhibitors and uses thereof PIC Therapeutics, Inc. (US) 2023-09-12 US disclosed
US-20230265173-A1 SULFONAMIDE-CONTAINING LINKAGE SYSTEMS FOR DRUG CONJUGATES ZYMEWORKS BC INC. (CA) 2023-08-24 US disclosed
US-20230265173-A1 SULFONAMIDE-CONTAINING LINKAGE SYSTEMS FOR DRUG CONJUGATES ZYMEWORKS BC INC. (CA) 2023-08-24 US disclosed
US-20230174485-A1 LIPOXYGENASE INHIBITORS SRI INTERNATIONAL (US) 2023-06-08 US disclosed
US-20230174485-A1 LIPOXYGENASE INHIBITORS SRI INTERNATIONAL (US) 2023-06-08 US disclosed
US-11661403-B2 Oxadiazole compounds VIVACE THERAPEUTICS, INC. (US) 2023-05-30 US disclosed
US-11661403-B2 Oxadiazole compounds VIVACE THERAPEUTICS, INC. (US) 2023-05-30 US disclosed
US-20230136150-A1 Compositions for Inhibition of Insect Sensing UNIV VANDERBILT (US) 2023-05-04 US disclosed
US-20060210922-A1 Positive resist composition and pattern forming method using the resist composition FUJI PHOTO FILM CO., LTD. 2006-09-21 US disclosed
EP-1703322-A2 Positive resist composition and pattern forming method using the resist composition FUJI PHOTO FILM CO., LTD. (JP) 2006-09-20 EP disclosed
US-20050186503-A1 Resist composition for immersion exposure and pattern formation method using the same FUJI PHOTO FILM CO., LTD. 2005-08-25 US disclosed
EP-1566693-A2 Resist composition for immersion exposure and pattern forming method using the same FUJI PHOTO FILM CO., LTD. (JP) 2005-08-24 EP disclosed
WO-2001051529-A1 PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
US-5001263-A Formation of ortho-alkylated aromatic amines from N-alkylated aromatic amines AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-03-19 US disclosed
US-4925984-A REACTION WITH BROMINE IN SOLUTION ETHYL CORPORATION (US) 1990-05-15 US disclosed
US-4876377-A SELECTIVITY TO ORTHO POSITION, BY-PRODUCT INHIBITION AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-10-24 US disclosed
EP-0334332-A1 Ortho-alkylated aromatic amines via gamma alumina catalyst AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-09-27 EP disclosed
EP-0240018-A2 Alkylation of aromatic amines with olefins on partially dealuminated zeolites AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265173-A1 SULFONAMIDE-CONTAINING LINKAGE SYSTEMS FOR DRUG CONJUGATES MPST, TPST2, SULT1A1 L3MBTL1 1016/4885POLB 3762/4885TDP1 2877/4885
US-20230136150-A1 Compositions for Inhibition of Insect Sensing OR51E2, TRPA1, OR10J3 L3MBTL1 1987/4885POLB 4840/4885TDP1 4502/4885
US-20230399322-A1 EIF4E INHIBITORS AND USES THEREOF EIF4E, EIF4EBP1, EIF4A1 L3MBTL1 420/4885POLB 1778/4885TDP1 1025/4885
US-11753403-B2 EIF4E inhibitors and uses thereof EIF4E, EIF4EBP1, EIF4A1 L3MBTL1 420/4885POLB 1778/4885TDP1 1025/4885
US-20230174485-A1 LIPOXYGENASE INHIBITORS ALOX15B, ALOX12, ALOX15 L3MBTL1 1916/4885POLB 1410/4885TDP1 1140/4885
US-11661403-B2 Oxadiazole compounds YAP1, TEAD2, TEAD3 L3MBTL1 2096/4885POLB 1636/4885TDP1 2083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.