Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 7/20 | 0.43 |
| ▸ | HTR1D | P28221 | 7/20 | 0.43 |
| ▸ | HTR1B | P28222 | 7/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 7/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6393258 | 0.88 | HTT (0.47) | CYP2C9CYP2C19CYP3A4GRM5HTR1A | |
| SCHEMBL6393501 | 0.86 | RIPK1 (0.42) | CYP2C9CYP2C19CYP3A4GRM5HTR1A | |
| SCHEMBL6391869 | 0.85 | HTR1A (0.47) | CYP2C9CYP2C19CYP3A4GRM5HTR1A | |
| SCHEMBL6392491 | 0.85 | RIPK1 (0.42) | CYP2C9CYP2C19CYP3A4GRM5HTR1A | |
| SCHEMBL6393526 | 0.85 | REN (0.45) | CYP2C9CYP2C19CYP3A4GRM5HTR1A | |
| SCHEMBL6178668 | 0.82 | RIPK1 (0.47) | CYP2C9CYP2C19CYP3A4GRM5HTR1A | |
| SCHEMBL6395028 | 0.77 | GRM5 (0.50) | CYP2C9CYP2C19CYP3A4GRM5RIPK1 | |
| SCHEMBL23076327 | 0.76 | RIPK1 (0.48) | CYP2C9CYP2C19CYP3A4GRM5RIPK1 | |
| SCHEMBL6426996 | 0.76 | GRM5 (0.44) | CYP2C9CYP2C19CYP3A4GRM5RIPK1 | |
| SCHEMBL6168702 | 0.73 | HTT (0.45) | CYP2C9CYP2C19CYP3A4HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165011-A1 | Benzoxazine and benzoxazinone substituted triazoles | GELLIBERT FRANCOISE J (FR) | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165011-A1 | Benzoxazine and benzoxazinone substituted triazoles | ACVR1, TGFBR1, SMAD3 | CYP2C9 3071/4885CYP2C19 2960/4885CYP3A4 1867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.