Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 4/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5074783 | 0.79 | GSK3B (0.50) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL30609814 | 0.79 | KDM4E (0.45) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL11604127 | 0.79 | GSK3B (0.39) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL10335607 | 0.79 | ALDH1A1 (0.42) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL21111964 | 0.79 | KDM4E (0.44) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL2359302 | 0.79 | GSK3B (0.42) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL11588296 | 0.77 | SOAT1 (0.42) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL30091416 | 0.76 | GSK3B (0.50) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL7078965 | 0.76 | GSK3B (0.50) | GSK3BALDH1A1KDM4EGAAHPGD | |
| SCHEMBL28236805 | 0.75 | MAOA (0.54) | GSK3BALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6946458-B2 | N-thiolated beta-lactams: novel antibacterial agents for methicillin-resistant Staphylococcus aureus | UNIVERSITY OF SOUTH FLORIDA (US) | 2005-09-20 | — | — | US | disclosed |
| US-20030191108-A1 | N-thiolated beta-lactams: novel antibacterial agents for methicillin-resistant staphylococcus aureus | SOUTH FLORIDA, UNIVERSITY OF | 2003-10-09 | — | — | US | disclosed |
| US-4427439-A | Composition for plant growth regulation | GAF CORPORATION (US) | 1984-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191108-A1 | N-thiolated beta-lactams: novel antibacterial agents for methicillin-resistant staphylococcus aureus | AAAS, TST, NRDC | GSK3B 1177/4885ALDH1A1 2378/4885KDM4E 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.