Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.48 |
| ▸ | HTR3B | O95264 | 4/20 | 0.48 |
| ▸ | HTR3A | P46098 | 4/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001880 | 0.69 | DRD2 (0.40) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Quipazine SCHEMBL322181 | 0.65 | KDM4E (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Quipazine SCHEMBL4062074 | 0.64 | KDM4E (0.97) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5001473 | 0.63 | DRD2 (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6242154 | 0.62 | HTR3E (0.68) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3836811 | 0.62 | DRD2 (0.45) | ALDH1A1KDM4EHTR2CHSD17B10SLC6A4 | |
| SCHEMBL4742301 | 0.62 | TRPA1 (0.50) | ALDH1A1KDM4ECYP3A4HTR2CHSD17B10 | |
| SCHEMBL1479055 | 0.61 | HTR3A (0.66) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3227424 | 0.61 | KDM4E (0.88) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30146590 | 0.60 | HTR3E (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890919-B2 | Atypical antipsychotic agents having low affinity for the D2 receptor | KAPUR SHITIJ (CA) | 2005-05-10 | — | — | US | disclosed |