SCHEMBL6400246

SCHEMBL6400246

Cc1cc(C)c(C(=O)[P](=O)C(C)C(=O)c2c(C)cc(C(C)(C)C)cc2C)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RXRB P28702 2/20 0.33
RXRA P19793 1/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HPGD P15428 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
POLB P06746 1/20 0.30
HMGCR P04035 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5995832 1.00 RXRB (0.33) RXRBRXRAKDM4EL3MBTL1HPGD
SCHEMBL5993538 0.95 RXRB (0.33) RXRBRXRAHPGDPOLBHMGCR
SCHEMBL5997841 0.89 ACHE (0.36) RXRBRXRAL3MBTL1
SCHEMBL5995853 0.89 ACHE (0.36) RXRBRXRAL3MBTL1
SCHEMBL5996056 0.87 ALDH1A1 (0.34) NPSR1
SCHEMBL6402169 0.84 HPGD (0.37) L3MBTL1HPGDNPSR1MCOLN3
SCHEMBL5997547 0.84 HPGD (0.37) L3MBTL1HPGDNPSR1MCOLN3
SCHEMBL5995876 0.83 ACLY (0.33)
SCHEMBL5995203 0.82 RAB9A (0.36) RXRBRXRAL3MBTL1NPSR1POLB
SCHEMBL5994057 0.81 ACHE (0.33) RXRBRXRAHPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 RXRB 550/4885RXRA 440/4885KDM4E 3308/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 RXRB 1585/4885RXRA 1279/4885KDM4E 2655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.