Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | CFD | P00746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | GGT1 | P19440 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL16599421 | 0.99 | KDM4E (0.51) | KDM4ECFDALDH1A1HSD17B10HPGD | |
| SCHEMBL6401897 | 0.89 | CFD (0.65) | KDM4ECFDALDH1A1HSD17B10HPGD | |
| SCHEMBL4959789 | 0.85 | PTGS2 (0.49) | KDM4ECFDALDH1A1HSD17B10HPGD | |
| SCHEMBL3130799 | 0.84 | PTGS2 (0.53) | KDM4ECFDALDH1A1HSD17B10HPGD | |
| Aspirin SCHEMBL4160555 | 0.81 | PTGS2 (0.53) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| Aspirin SCHEMBL4160561 | 0.81 | PTGS2 (0.53) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL17986280 | 0.80 | TSHR (0.42) | KDM4ECFDALDH1A1HSD17B10PTGS2 | |
| SCHEMBL16719152 | 0.79 | CFD (0.76) | KDM4ECFDALDH1A1HSD17B10HPGD | |
| SCHEMBL16599538 | 0.78 | KDM4E (0.47) | KDM4ECFDALDH1A1HSD17B10HPGD | |
| SCHEMBL17986190 | 0.77 | PTGS2 (0.46) | KDM4EALDH1A1HSD17B10PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148554-A1 | Anti-inflammatory and anti-thrombotic compounds and their compositions | ZHANG DON (US) | 2005-07-07 | — | — | US | disclosed |
| WO-2004062598-A2 | ANTI-INFLAMMATORY AND ANTI-THROMBOTIC COMPOUNDS AND THEIR COMPOSITIONS | BETA PHARMA, INC. (US) | 2004-07-29 | — | — | WO | disclosed |
| EP-1147074-A1 | SYNTHESIS METHOD OF NITROXYMETHYLPHENYL ESTERS OF ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000044705-A1 | SYNTHESIS METHOD OF NITROXYMETHYLPHENYL ESTERS OF ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2000-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148554-A1 | Anti-inflammatory and anti-thrombotic compounds and their compositions | PTGS1, PTGS2, PTGER1 | KDM4E 3180/4885CFD 117/4885ALDH1A1 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.