Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 7/20 | 0.50 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.48 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLR1A | O95602 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5886437 | 0.83 | RAD52 (0.56) | RAD52SMARCA2AOX1UHRF1ALDH1A1 | |
| SCHEMBL5886330 | 0.77 | RAD52 (0.64) | RAD52SMARCA2AOX1UHRF1ALDH1A1 | |
| SCHEMBL5886272 | 0.76 | RAD52 (0.70) | RAD52SMARCA2AOX1UHRF1ALDH1A1 | |
| SCHEMBL5886529 | 0.75 | RAD52 (0.78) | RAD52SMARCA2AOX1UHRF1ALDH1A1 | |
| SCHEMBL5886543 | 0.75 | RAD52 (0.61) | RAD52SMARCA2AOX1UHRF1ALDH1A1 | |
| SCHEMBL5886244 | 0.74 | RAD52 (0.67) | RAD52SMARCA2AOX1UHRF1ALDH1A1 | |
| SCHEMBL5886306 | 0.74 | RAD52 (0.57) | RAD52SMARCA2AOX1UHRF1ALDH1A1 | |
| SCHEMBL7063204 | 0.73 | RAD52 (0.69) | RAD52SMARCA2AOX1UHRF1ALDH1A1 | |
| SCHEMBL5886332 | 0.73 | RAD52 (0.58) | RAD52SMARCA2AOX1UHRF1ALDH1A1 | |
| SCHEMBL5886580 | 0.71 | RAD52 (0.57) | RAD52SMARCA2AOX1UHRF1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143383-A1 | Pharmaceutical compounds | XENOVA LIMITED (GB) | 2005-06-30 | — | — | US | claimed |
| US-20030139409-A1 | Benzo[A] [phenazin-11-carboxamide derivatives and their use as joint inhibitors of topomerase I and II | XENOVA LIMITED (GB) | 2003-07-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143383-A1 | Pharmaceutical compounds | CHRNA10, OPRM1, SCN10A | RAD52 2083/4885SMARCA2 1543/4885AOX1 1216/4885 |
| US-20030139409-A1 | Benzo[A] [phenazin-11-carboxamide derivatives and their use as joint inhibitors of topomerase I and II | TOP1, TOP2A, TOP2B | RAD52 60/4885SMARCA2 1456/4885AOX1 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.