Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401395 | 1.00 | CYP19A1 (0.49) | CYP19A1ACHEMTNR1AMTNR1BKDM4E | |
| SCHEMBL7272139 | 0.90 | LMNA (0.58) | CYP19A1ACHEMTNR1AMTNR1BKDM4E | |
| SCHEMBL8765833 | 0.86 | ACHE (0.58) | CYP19A1ACHEMTNR1AMTNR1BLMNA | |
| SCHEMBL7280376 | 0.86 | MTNR1A (0.52) | CYP19A1ACHEMTNR1AMTNR1BNQO2 | |
| SCHEMBL12256769 | 0.85 | SMN1; SMN2 (0.53) | ACHEKDM4EMAPTLMNAPOLB | |
| Ethylene SCHEMBL8765917 | 0.84 | ACHE (0.56) | CYP19A1ACHEMTNR1AMTNR1BLMNA | |
| SCHEMBL8307518 | 0.84 | KDM4E (0.43) | KDM4EMAPTLMNAPOLBNPC1 | |
| SCHEMBL345475 | 0.78 | ACHE (0.51) | CYP19A1ACHEMTNR1AMTNR1BCA1 | |
| SCHEMBL1877585 | 0.77 | ACHE (0.52) | CYP19A1ACHEMTNR1AMTNR1BKDM4E | |
| SCHEMBL7979383 | 0.77 | CYP19A1 (0.55) | CYP19A1ACHEMTNR1AMTNR1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050153408-A1 | 7-substituted-2-tetralone or bisulfite adduct is reduced microorganism (Candida) to optically active 7-substituted-2-tetralol;sulfonyl group is introduced to hydroxy group to form optically active 7-substituted-2-sulfonyloxytetralin; nitrogen substituent is introduced via ammonia; industrial scale | KANEKA CORPORATION (JP) | 2005-07-14 | — | — | US | disclosed |
| EP-1457570-A1 | PROCESS FOR PREPARATION OF 2-AMINOTETRALIN DERIVATIVES AND INTERMEDIATES THEREOF | KANEKA CORPORATION (JP) | 2004-09-15 | — | — | EP | disclosed |