Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.60 |
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.48 |
| ▸ | METAP2 | P50579 | 2/20 | 0.48 |
| ▸ | METAP1 | P53582 | 2/20 | 0.48 |
| ▸ | CBFB | Q13951 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | TCF4 | P15884 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | KCNK13 | Q9HB14 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26922233 | 0.89 | SMN1; SMN2 (0.65) | ALDH1A1HPGDSMN1; SMN2NPSR1RPS6KA5 | |
| SCHEMBL30612244 | 0.89 | SMN1; SMN2 (0.65) | ALDH1A1HPGDSMN1; SMN2NPSR1RPS6KA5 | |
| SCHEMBL26921422 | 0.83 | ALDH1A1 (0.65) | ALDH1A1HPGDSMN1; SMN2NPSR1RPS6KA5 | |
| SCHEMBL1901356 | 0.80 | HPGD (0.60) | ALDH1A1HPGDSMN1; SMN2NPSR1RPS6KA5 | |
| SCHEMBL1160565 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HPGDSMN1; SMN2NPSR1RPS6KA5 | |
| SCHEMBL4006784 | 0.78 | METAP2 (0.56) | AMY1AMETAP2METAP1CBFBCYP11B1 | |
| SCHEMBL6406163 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HPGDSMN1; SMN2NPSR1RPS6KA5 | |
| SCHEMBL26922855 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2NPSR1RPS6KA5 | |
| SCHEMBL1901797 | 0.77 | ALDH1A1 (0.68) | ALDH1A1HPGDSMN1; SMN2NPSR1RPS6KA5 | |
| SCHEMBL14364577 | 0.77 | HPGD (0.60) | ALDH1A1HPGDSMN1; SMN2NPSR1RPS6KA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158385-A1 | NOVEL COMPOUNDS | Cerevance, Inc. | 2024-05-16 | — | — | US | disclosed |
| EP-4288433-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-116981665-A | Novel compounds | 思瑞万斯公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2022167819-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2022-08-11 | — | — | WO | disclosed |
| US-20050153978-A1 | Medicaments | GLAXO GROUP LIMITED (GB) | 2005-07-14 | — | — | US | disclosed |
| EP-1487441-A2 | BENZIMIDAZOLES AND THEIR USE AS MITOGEN-ACTIVATED- AND RHO-KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080125-A2 | BENZIMIDAZOLES AND THEIR USE AS MITOGEN-ACTIVATED- AND RHO-KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158385-A1 | NOVEL COMPOUNDS | KCNK3, KCNA4, KCNK13 | ALDH1A1 2143/4885HPGD 1524/4885SMN1; SMN2 1585/4885 |
| US-20050153978-A1 | Medicaments | GRK1, ROCK1, GRK7 | ALDH1A1 4488/4885HPGD 3802/4885SMN1; SMN2 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.