SCHEMBL6401609

SCHEMBL6401609

C=[Zr](Cl)(Cl)(C1C=C(C(C2CCCCC2)C2CCCCC2)c2ccccc21)C1C=C(C(C2CCCCC2)C2CCCCC2)c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
IDO1 P14902 9/20 0.30
TDO2 P48775 5/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2B6 P20813 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6401878 0.99 BCHE (0.33) BCHEACHE
SCHEMBL6406840 0.93
SCHEMBL6409022 0.84 BCHE (0.34) BCHEACHE
SCHEMBL6401691 0.84 BCHE (0.34) BCHEACHE
SCHEMBL6402574 0.84 BCHE (0.34) BCHEACHE
SCHEMBL6406820 0.83 BCHE (0.33) BCHEACHEIDO1TDO2CYP3A4
SCHEMBL6407291 0.82 BCHE (0.32) BCHEACHE
SCHEMBL6402658 0.81 IDO1 (0.31) BCHEACHEIDO1TDO2
SCHEMBL6405880 0.80
SCHEMBL6403261 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1017729-B1 PROCESS FOR THE PREPARATION OF SUBSTANTIALLY AMORPHOUS ALPHA-OLEFIN POLYMERS, COMPOSITIONS CONTAINING THEM AND PROCESS FOR THE PREPARATION OF BRIDGED LIGAND BASELL POLYOLEFINE GMBH (DE) 2005-09-14 EP disclosed
US-6844288-B2 Process for the preparation of ligands for metallogene catalysts BASELL POLYOLEFINE GMBH (DE) 2005-01-18 US disclosed
EP-0991677-B1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH ALPHA-OLEFINS BASELL POLYOLEFINE GMBH (DE) 2004-06-16 EP disclosed
US-20030158356-A1 Process for the preparation of substantially amorphous alpha-olefin polymers and compositions containing them and process for the preparation of bridged ligand EQUISTAR CHEMICALS, LP 2003-08-21 US disclosed
US-20020169260-A1 Process for the preparation of ligands for metallocene catalysts RESCONI LUIGI (IT) 2002-11-14 US disclosed
US-20020156209-A1 Polymerization in the presence of metallocene catalysts with bridged bis-indenyl compounds BASELL TECHNOLOGY COMANY BV (NL) 2002-10-24 US disclosed
US-6448350-B1 Process for the preparation of copolymers of ethylene with alpha-olefins BASELL TECHNOLOGY COMPANY BV (NL) 2002-09-10 US disclosed
US-6423796-B1 COORDINATION CATALYST BASEL TECHNOLOGY COMPANY BV (NL) 2002-07-23 US disclosed
WO-2000001738-A9 PROCESS FOR THE PREPARATION OF SUBSTANTIALLY AMORPHOUS ALPHA-OLEFIN POLYMERS, COMPOSITIONS CONTAINING THEM AND PROCESS FOR THE PREPARATION OF BRIDGED LIGAND MONTELL TECHNOLOGY COMPANY BV (NL) 2000-07-27 WO disclosed
EP-1017729-A2 PROCESS FOR THE PREPARATION OF SUBSTANTIALLY AMORPHOUS ALPHA-OLEFIN POLYMERS, COMPOSITIONS CONTAINING THEM AND PROCESS FOR THE PREPARATION OF BRIDGED LIGAND Montell Technology Company bv (NL) 2000-07-12 EP disclosed
EP-0991677-A1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH ALPHA-OLEFINS Montell Technology Company bv (NL) 2000-04-12 EP disclosed
WO-2000001738-A2 PROCESS FOR THE PREPARATION OF SUBSTANTIALLY AMORPHOUS ALPHA-OLEFIN POLYMERS, COMPOSITIONS CONTAINING THEM AND PROCESS FOR THE PREPARATION OF BRIDGED LIGAND MONTELL TECHNOLOGY COMPANY BV (NL) 2000-01-13 WO disclosed
WO-1999054369-A1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH ALPHA-OLEFINS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1999-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030158356-A1 Process for the preparation of substantially amorphous alpha-olefin polymers and compositions containing them and process for the preparation of bridged ligand MACF1, SDC1, SDC2 BCHE 4211/4885ACHE 4508/4885IDO1 482/4885
US-20020169260-A1 Process for the preparation of ligands for metallocene catalysts SDC1, SDC2, SDC4 BCHE 4513/4885ACHE 4573/4885IDO1 1084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.