SCHEMBL6402

SCHEMBL6402

O=C(O)c1cccc([N+](=O)[O-])c1F

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.64
TDP1 Q9NUW8 3/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 2/20 0.49
MAPT P10636 2/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
GAA P10253 1/20 0.49
KMT2A Q03164 1/20 0.49
GPR35 Q9HC97 1/20 0.48
DNA2 P51530 1/20 0.48
CASP6 P55212 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
CTSD P07339 1/20 0.46
CDC25B P30305 1/20 0.46
DTYMK P23919 1/20 0.45
POLB P06746 1/20 0.45
LMNA P02545 1/20 0.44
HTT P42858 1/20 0.44
ALB P02768 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29025719 0.85 TSHR (0.50) TSHRTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL38654770 0.84 TSHR (0.49) TSHRTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL7859174 0.84 TSHR (0.53) TSHRTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL6292 0.84 TSHR (0.49) TSHRTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL13606472 0.84 TSHR (0.49) TSHRTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL22070445 0.83 DTYMK (0.50) TSHRTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL9882444 0.83 TSHR (0.51) TSHRTDP1L3MBTL1ALDH1A1KDM4E
SCHEMBL14956593 0.83 ALDH1A1 (0.50) TSHRTDP1ALDH1A1MAPTKDM4E
Hydrochloric Acid SCHEMBL28210415 0.82 TSHR (0.47) TSHRTDP1L3MBTL1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL21693740 0.82 TSHR (0.47) TSHRTDP1L3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 828 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574054-B Preparation method of 2-fluoro-3-nitrobenzoic acid 济南国鼎医药科技有限公司 2026-05-15 CN claimed
CN-122010739-A Synthesis method of 2-fluoro-3-nitrobenzoic acid 山东佰隆医药有限公司 2026-05-12 CN claimed
CN-121574054-A Preparation method of 2-fluoro-3-nitrobenzoic acid 济南国鼎医药科技有限公司 2026-02-27 CN claimed
CN-119954678-A Preparation method and application of diamide compound with insecticidal high activity 山东华升新材料有限公司 2025-05-09 CN claimed
CN-114560774-B Synthesis method of 2-fluoro-3-nitrobenzoic acid 九洲药业(杭州)有限公司 2025-05-06 CN claimed
CN-119823035-A Preparation method of m-aminobenzoic acid bisamide compound 湖南化工研究院有限公司 2025-04-15 CN claimed
CN-119775143-A Synthesis method of 2-fluoro-3-nitrobenzoic acid 河北科技大学 2025-04-08 CN claimed
CN-118271177-B Production process of 2-fluoro-3-nitrobenzoic acid 山东极地医药科技有限公司 2024-10-25 CN claimed
CN-118812209-A Preparation method of polyvinyl alcohol emulsion modified cement paste generated in situ 海南大学 2024-10-22 CN claimed
CN-118621569-A Polyvinyl alcohol fiber surface acetalation modification method 海南大学 2024-09-10 CN claimed
CN-113717053-A Synthesis method of key intermediate of tyrosine kinase inhibitor 合肥利夫生物科技有限公司 2021-11-30 CN claimed
US-11180443-B2 Preparation method for m-diamide compounds CAC NANTONG CHEMICAL CO., LTD (CN) 2021-11-23 US claimed
CN-113501807-A Tetrahydrobenzothiophene compound, and preparation method and application of pharmaceutical composition 重庆科技学院 2021-10-15 CN claimed
CN-113024384-A Synthesis method of 2-fluoro-3-nitrobenzoic acid intermediate raw material 湖南工程学院 2021-06-25 CN claimed
US-20210122707-A1 PREPARATION METHOD FOR M-DIAMIDE COMPOUNDS CAC NANTONG CHEMICAL CO., LTD (CN) 2021-04-29 US claimed
EP-3812366-A1 A PREPARATION METHOD FOR M-DIAMIDE COMPOUNDS CAC Nantong Chemical Co., Ltd. (CN) 2021-04-28 EP claimed
CN-112707836-A Preparation method of m-diamide compound 南通泰禾化工股份有限公司 2021-04-27 CN claimed
CN-108218709-A The separation method of the fluoro- benzoic acid nitration products of the chloro- 4- of 2- 江苏联化科技有限公司 2018-06-29 CN claimed
CN-103922942-B The preparation method of the fluoro-3-nitrobenzoic acid of a kind of chloro-5-of 2,4-bis- DALIAN QIKAI MEDICAL TECHNOLOGY CO., LTD. (CN) 2016-05-04 CN claimed
CN-103922942-A Preparation method of 2, 4-dichloro-5-fluoro-3-nitrobenzoic acid DALIAN QIKAI MEDICAL TECHNOLOGY CO LTD 2014-07-16 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11180443-B2 Preparation method for m-diamide compounds ACR, PMP22, PFAS TSHR 3331/4885TDP1 1273/4885L3MBTL1 2015/4885
US-20210122707-A1 PREPARATION METHOD FOR M-DIAMIDE COMPOUNDS ACR, PMP22, PFAS TSHR 3331/4885TDP1 1273/4885L3MBTL1 2015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.