SCHEMBL6292

SCHEMBL6292

O=C(Cl)c1cccc([N+](=O)[O-])c1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.49
CTSD P07339 1/20 0.49
ALDH1A1 P00352 4/20 0.47
GPR35 Q9HC97 3/20 0.47
ALOX15 P16050 1/20 0.46
TDP1 Q9NUW8 4/20 0.44
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
MAPK13 O15264 1/20 0.42
MAPK12 P53778 1/20 0.42
MAPK11 Q15759 1/20 0.42
MAPK14 Q16539 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
DHODH Q02127 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38654770 1.00 TSHR (0.49) TSHRCTSDALDH1A1GPR35ALOX15
Hydrochloric Acid SCHEMBL21693740 0.98 TSHR (0.47) TSHRCTSDALDH1A1GPR35ALOX15
Acetonitrile SCHEMBL28729784 0.91 TSHR (0.45) TSHRCTSDALDH1A1GPR35ALOX15
SCHEMBL6402 0.84 TSHR (0.64) TSHRCTSDALDH1A1GPR35TDP1
SCHEMBL29025719 0.84 TSHR (0.50) TSHRCTSDALDH1A1GPR35TDP1
SCHEMBL13606472 0.82 TSHR (0.49) TSHRCTSDALDH1A1GPR35TDP1
SCHEMBL7859174 0.82 TSHR (0.53) TSHRCTSDALDH1A1GPR35TDP1
SCHEMBL1456960 0.81 GPR35 (0.67) TSHRCTSDALDH1A1GPR35TDP1
SCHEMBL103644 0.81 CTSD (0.65) TSHRCTSDALDH1A1TDP1CYP3A4
SCHEMBL6999946 0.81 MAPT (0.49) TSHRCTSDALDH1A1GPR35TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823035-A Preparation method of m-aminobenzoic acid bisamide compound 湖南化工研究院有限公司 2025-04-15 CN claimed
CN-118164976-A 2- (7-Benzothiazolyl) benzo heterocycle compound and application thereof 沈阳中化农药化工研发有限公司 2024-06-11 CN claimed
CN-118164923-A Benzo five-membered heterocyclic compound and application thereof 沈阳中化农药化工研发有限公司 2024-06-11 CN claimed
CN-112707836-B Preparation method of m-diamide compound 南通泰禾化工股份有限公司 2022-10-14 CN claimed
EP-3812366-B1 A PREPARATION METHOD FOR M-DIAMIDE COMPOUNDS CAC NANTONG CHEMICAL CO LTD (CN) 2022-02-16 EP claimed
US-11180443-B2 Preparation method for m-diamide compounds CAC NANTONG CHEMICAL CO., LTD (CN) 2021-11-23 US claimed
US-20210122707-A1 PREPARATION METHOD FOR M-DIAMIDE COMPOUNDS CAC NANTONG CHEMICAL CO., LTD (CN) 2021-04-29 US claimed
EP-3812366-A1 A PREPARATION METHOD FOR M-DIAMIDE COMPOUNDS CAC Nantong Chemical Co., Ltd. (CN) 2021-04-28 EP claimed
CN-112707836-A Preparation method of m-diamide compound 南通泰禾化工股份有限公司 2021-04-27 CN claimed
CN-101351443-B Process for preparing sulfonamides BASF SE 2012-11-28 CN claimed
CN-101351443-A Process for preparing sulfonamides BASF AG (DE) 2009-01-21 CN claimed
CN-122079811-A Cyclopropylmethoxybenzamide compound, and preparation method and application thereof 2026-05-26 CN disclosed
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES UNIV YALE (US) 2026-04-30 US disclosed
US-12497351-B2 3-N-cyclopropylmethyl-2-fluorobenzamide compound, preparation method therefor and use thereof CAC NANTONG CHEMICAL CO., LTD (CN) 2025-12-16 US disclosed
EP-3684181-B1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2025-10-22 EP disclosed
WO-2010127928-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2010-11-11 WO disclosed
CN-101351443-A Process for preparing sulfonamides BASF AG (DE) 2009-01-21 CN disclosed
CN-1185229-C 3-indolyl-4-phenyl-1H-pyrrole-2, 5-dione derivatives as glycogen synthase kinase-3 beta inhibitors HOFFMANN LA ROCHE (CH) 2005-01-19 CN disclosed
CN-1444581-A 3-indolyl-4-phenyl-1H-pyrrole-2, 5-dione derivatives as inhibitors of glycogen synthase kinase-3beta HOFFMANN LA ROCHE (CH) 2003-09-24 CN disclosed
WO-2002072567-A2 HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLENMARK PHARMACEUTICALS LIMITED (IN) 2002-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12497351-B2 3-N-cyclopropylmethyl-2-fluorobenzamide compound, preparation method therefor and use thereof CYP51A1, DDT, CYP4F11 TSHR 4052/4885CTSD 1679/4885ALDH1A1 423/4885
US-11180443-B2 Preparation method for m-diamide compounds ACR, PMP22, PFAS TSHR 3331/4885CTSD 3329/4885ALDH1A1 2786/4885
US-20210122707-A1 PREPARATION METHOD FOR M-DIAMIDE COMPOUNDS ACR, PMP22, PFAS TSHR 3331/4885CTSD 3329/4885ALDH1A1 2786/4885
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES CRBN, VHL, ADRM1 TSHR 1899/4885CTSD 2916/4885ALDH1A1 2777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.