Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6402278 | 0.89 | HDAC6 (0.57) | POLBNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL6410519 | 0.88 | NPC1 (0.59) | POLBPPARGNPC1RAB9AMAPK1 | |
| SCHEMBL6403903 | 0.82 | PPARG (0.55) | POLBKMT2APPARGNPC1RAB9A | |
| SCHEMBL6402495 | 0.81 | HPGD (0.56) | POLBKCNK3KCNK9PPARGNPC1 | |
| SCHEMBL6408049 | 0.81 | NPC1 (0.55) | POLBMEN1KMT2AKCNK9NPC1 | |
| SCHEMBL6403554 | 0.80 | POLB (0.58) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL259666 | 0.77 | KCNK3 (0.87) | POLBMEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL30608967 | 0.77 | KCNK3 (0.87) | POLBMEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL6407778 | 0.76 | HSD17B10 (0.62) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL6403162 | 0.75 | POLB (0.54) | POLBMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101528737-B | Novel heteroaryl carboxamides | HOFFMANN LA ROCHE | 2012-07-04 | — | — | CN | disclosed |
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | POLB 3713/4885MEN1 3154/4885KMT2A 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.