Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6402278 | 0.84 | HDAC6 (0.57) | SMN1; SMN2NPC1RAB9APOLBMAPK1 | |
| SCHEMBL6410519 | 0.83 | NPC1 (0.59) | HPGDSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL6402219 | 0.81 | POLB (0.55) | SMN1; SMN2NPC1RAB9APOLBMAPK1 | |
| SCHEMBL6410595 | 0.81 | HPGD (0.51) | HPGDSMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL6403903 | 0.80 | PPARG (0.55) | SMN1; SMN2NPC1RAB9APOLBMAPK1 | |
| SCHEMBL6408049 | 0.78 | NPC1 (0.55) | HPGDSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL21993 | 0.74 | HPGD (1.00) | HPGDSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL8266868 | 0.73 | RAB9A (0.77) | SMN1; SMN2NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL6408618 | 0.71 | SMN1; SMN2 (0.62) | HPGDSMN1; SMN2NPC1RAB9APOLB | |
| Iodomethane SCHEMBL20530190 | 0.71 | HPGD (0.93) | HPGDSMN1; SMN2NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101528737-B | Novel heteroaryl carboxamides | HOFFMANN LA ROCHE | 2012-07-04 | — | — | CN | disclosed |
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | HPGD 3244/4885SMN1; SMN2 4458/4885NPC1 1915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.