Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11122001 | 0.84 | TSHR (0.41) | THRBTSHRALDH1A1APEX1EPHX1 | |
| SCHEMBL8767187 | 0.81 | ACHE (0.37) | THRBALDH1A1EPHX1ACHE | |
| Butadiene SCHEMBL1685979 | 0.80 | THRB (0.63) | THRBTSHRALDH1A1APEX1POLB | |
| Propene SCHEMBL7154370 | 0.80 | THRB (0.63) | THRBTSHRALDH1A1APEX1POLB | |
| Propene SCHEMBL11112032 | 0.80 | THRB (0.63) | THRBTSHRALDH1A1APEX1POLB | |
| Propene SCHEMBL8851515 | 0.80 | THRB (0.63) | THRBTSHRALDH1A1APEX1POLB | |
| Propene SCHEMBL672400 | 0.80 | THRB (0.63) | THRBTSHRALDH1A1APEX1POLB | |
| Propene SCHEMBL3343927 | 0.80 | THRB (0.63) | THRBTSHRALDH1A1APEX1POLB | |
| Propene SCHEMBL156576 | 0.80 | THRB (0.63) | THRBTSHRALDH1A1APEX1POLB | |
| Propene SCHEMBL8850806 | 0.80 | THRB (0.63) | THRBTSHRALDH1A1APEX1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345773-B2 | Water extractable ophthalmic devices | BAUSCH & LOMB INCORPORATED (US) | 2022-05-31 | — | — | US | disclosed |
| US-11022722-B2 | Water extractable ophthalmic devices | BAUSCH & LOMB INCORPORATED (US) | 2021-06-01 | — | — | US | disclosed |
| US-20190352443-A1 | WATER EXTRACTABLE OPHTHALMIC DEVICES | BAUSCH HEALTH AMERICAS, INC. | 2019-11-21 | — | — | US | disclosed |
| US-8119753-B2 | Silicone hydrogels with amino surface groups | BAUSCH & LOMB INCORPORATED (US) | 2012-02-21 | — | — | US | disclosed |
| EP-2207852-A1 | SILICONE HYDROGELS WITH AMINO SURFACE GROUPS | Bausch & Lomb Incorporated (US) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009055226-A1 | SILICONE HYDROGELS WITH AMINO SURFACE GROUPS | BAUSCH & LOMB INCORPORATED (US) | 2009-04-30 | — | — | WO | disclosed |
| US-20090103045-A1 | SILICONE HYDROGELS WITH AMINO SURFACE GROUPS | SALIX PHARMACEUTICALS, INC. | 2009-04-23 | — | — | US | disclosed |