SCHEMBL6402416

SCHEMBL6402416

CC#COC(C)c1ccc(OC)c(OC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.50
PPARD Q03181 1/20 0.50
PPARA Q07869 1/20 0.50
ACHE P22303 6/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 5/20 0.40
TSHR P16473 1/20 0.40
RAB9A P51151 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HTT P42858 1/20 0.39
CA12 O43570 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7063350 0.77 ACHE (0.50) PPARGPPARDPPARAACHECA1
SCHEMBL3649536 0.76 PPARG (0.46) PPARGPPARDPPARAACHECA1
SCHEMBL29359121 0.76 PPARG (0.46) PPARGPPARDPPARAACHECA1
SCHEMBL7773862 0.73 PPARG (0.44) PPARGPPARDPPARAACHECA1
SCHEMBL84033 0.73 PPARG (0.53) PPARGPPARDPPARAACHECA1
SCHEMBL7773629 0.71 L3MBTL1 (0.44) PPARGPPARDPPARAACHECA1
SCHEMBL13955907 0.71 PPARG (0.55) PPARGPPARDPPARAACHECA1
SCHEMBL7430435 0.71 PPARG (0.51) PPARGPPARDPPARAACHECA1
SCHEMBL670305 0.70 PPARG (0.59) PPARGPPARDPPARAACHECA1
SCHEMBL6779179 0.70 ACHE (0.50) PPARGPPARDPPARAACHECA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6881869-B1 Method for preparing substituted mixed alkynyl ethers RHODIA CHIMIE (FR) 2005-04-19 US claimed
EP-1216220-A1 METHOD FOR PREPARING SUBSTITUTED MIXED ALKYNYL ETHERS RHODIA CHIMIE (FR) 2002-06-26 EP claimed
WO-2001023338-A1 METHOD FOR PREPARING SUBSTITUTED MIXED ALKYNYL ETHERS RHODIA CHIMIE (FR) 2001-04-05 WO claimed
EP-1216220-A1 METHOD FOR PREPARING SUBSTITUTED MIXED ALKYNYL ETHERS RHODIA CHIMIE (FR) 2002-06-26 EP disclosed
WO-2001023338-A1 METHOD FOR PREPARING SUBSTITUTED MIXED ALKYNYL ETHERS RHODIA CHIMIE (FR) 2001-04-05 WO disclosed