Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28219379 | 0.82 | BCHE (0.48) | L3MBTL1ACHETDP1CYP1A2CYP2C9 | |
| SCHEMBL9662716 | 0.80 | MAPT (0.49) | L3MBTL1TDP1KMT2ANPSR1MAPT | |
| SCHEMBL7063350 | 0.79 | ACHE (0.50) | PPARGPPARDPPARAL3MBTL1CA2 | |
| SCHEMBL27501438 | 0.79 | ACHE (0.44) | PPARGPPARDPPARAL3MBTL1CA2 | |
| SCHEMBL12296384 | 0.79 | ACHE (0.48) | PPARGPPARDPPARAL3MBTL1CA2 | |
| Hydrochloric Acid SCHEMBL9661830 | 0.79 | MAPT (0.48) | L3MBTL1TDP1KMT2ANPSR1BLM | |
| SCHEMBL9535856 | 0.79 | PPARG (0.48) | PPARGPPARDPPARAL3MBTL1CA2 | |
| SCHEMBL84033 | 0.79 | PPARG (0.53) | PPARGPPARDPPARAL3MBTL1CA2 | |
| SCHEMBL9884522 | 0.78 | ALDH1A1 (0.46) | PPARGPPARDPPARAL3MBTL1CA2 | |
| SCHEMBL8298141 | 0.78 | ALDH1A1 (0.60) | PPARGPPARDPPARAL3MBTL1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956389-A | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS WITH N-METHYL-N-BIS(3,4-DIMETHOXYPHENYLETHYL)AMINE | YASON S.R.L. (IT) | 1990-09-11 | — | — | US | claimed |
| WO-1998004250-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE REVERSION OF MULTIPLE RESISTANCE TO DRUGS | CONSULTANTS INTERNATIONAUX SUR LE MEDICAMENT (S.A.R.L.) (FR) | 1998-02-05 | — | — | WO | disclosed |
| US-4956389-A | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS WITH N-METHYL-N-BIS(3,4-DIMETHOXYPHENYLETHYL)AMINE | YASON S.R.L. (IT) | 1990-09-11 | — | — | US | disclosed |