SCHEMBL6402981

SCHEMBL6402981

Nc1cccc(Oc2ccc(C(c3ccc(Oc4ccccc4N)cc3)(C(F)(F)F)C(F)(F)F)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.51
ALDH1A1 P00352 4/20 0.48
GAA P10253 3/20 0.48
RCE1 Q9Y256 1/20 0.47
MAPT P10636 4/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MITF O75030 1/20 0.41
GFER P55789 1/20 0.41
NLRP1 Q9C000 1/20 0.41
NOD2 Q9HC29 1/20 0.41
RAB9A P51151 2/20 0.41
POLB P06746 1/20 0.40
HSP90AA1 P07900 1/20 0.40
TLR4 O00206 1/20 0.39
IKBKB O14920 1/20 0.39
BRAF P15056 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31105162 1.00 MAOB (0.51) MAOBALDH1A1GAARCE1MAPT
SCHEMBL29371179 0.89 MAOB (0.59) MAOBALDH1A1GAAMAPTL3MBTL1
SCHEMBL127744 0.89 MAOB (0.59) MAOBALDH1A1GAAMAPTL3MBTL1
SCHEMBL29390225 0.89 MAOB (0.59) MAOBALDH1A1GAAMAPTL3MBTL1
SCHEMBL9651496 0.88 MAOA (0.46) MAOBALDH1A1GAARCE1MAPT
SCHEMBL6407132 0.88 MAOA (0.46) MAOBALDH1A1GAARCE1MAPT
Ammonia Solution, Strong SCHEMBL8591863 0.87 MAOB (0.58) MAOBALDH1A1GAAMAPTL3MBTL1
SCHEMBL653256 0.87 GAA (0.50) ALDH1A1GAARCE1MAPTL3MBTL1
SCHEMBL9742335 0.86 ALDH1A1 (0.58) MAOBALDH1A1GAAMAPTMEN1
SCHEMBL3465565 0.86 ALDH1A1 (0.58) MAOBALDH1A1GAAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9688815-B2 Method for producing polyimide precursor and method for producing polyimide RICOH COMPANY, LTD. (JP) 2017-06-27 US disclosed
US-20160122474-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICHO COMPANY, LTD. (JP) 2016-05-05 US disclosed
US-20120177425-A1 GLOSSY SURFACE FORMING APPARATUS AND GLOSSY SURFACE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-07-12 US disclosed
CN-1655075-A Intermediate transfer medium, film forming liquid for the intermediate transfer medium and image forming apparatus using intermediate transfer medium RICOH KK (JP) 2005-08-17 CN disclosed
US-20050136245-A1 Intermediate transfer medium, film forming liquid for the intermediate transfer medium and image forming apparatus using intermediate transfer medium RICOH COMPANY LIMITED (JP) 2005-06-23 US disclosed